User:Elizabeth A. Palumbo/Sandbox 1
From Proteopedia
< User:Elizabeth A. Palumbo(Difference between revisions)
(New page: ==Anaplastic Lymphoma Kinase== <StructureSection load='7N00' size='350' frame= 'true' side='right' caption='Anaplastic Lymphoma Kinase 7N00' scene=''> This is a default text for your page ...) |
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==Overall Structure== | ==Overall Structure== | ||
[[Image:Full_ALK_Structure.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]] | [[Image:Full_ALK_Structure.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]] | ||
| + | Structure provided by <ref name="Li">PMID:34819665</ref> | ||
===Dimerization=== | ===Dimerization=== | ||
===Conformational Changes=== | ===Conformational Changes=== | ||
| + | <ref name="Ransey">PMID:28504306</ref> | ||
==Ligands== | ==Ligands== | ||
===ALKAL1=== | ===ALKAL1=== | ||
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[http://https://en.wikipedia.org/wiki/Anaplastic_lymphoma_kinase Wikipedia] | [http://https://en.wikipedia.org/wiki/Anaplastic_lymphoma_kinase Wikipedia] | ||
==Function== | ==Function== | ||
| + | <scene name='90/906218/Random_selection/1'>Don't know</scene> | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Current revision
Anaplastic Lymphoma Kinase
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature. 2021 Dec;600(7887):148-152. doi: 10.1038/s41586-021-04141-7. Epub 2021, Nov 24. PMID:34819665 doi:http://dx.doi.org/10.1038/s41586-021-04141-7
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
