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7yyk
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the O-fucosylated form of TSRs1-3 from the human thrombospondin 1== | |
| + | <StructureSection load='7yyk' size='340' side='right'caption='[[7yyk]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7yyk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YYK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yyk OCA], [https://pdbe.org/7yyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yyk RCSB], [https://www.ebi.ac.uk/pdbsum/7yyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yyk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSP1_HUMAN TSP1_HUMAN] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:11134179</ref> <ref>PMID:15014436</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Thrombospondin|Thrombospondin]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hurtado-Guerrero | + | [[Category: Berardinelli SJ]] |
| - | [[Category: | + | [[Category: Eletsky A]] |
| - | [[Category: | + | [[Category: Haltiwanger RS]] |
| - | [[Category: | + | [[Category: Hurtado-Guerrero R]] |
| - | [[Category: | + | [[Category: Ito A]] |
| + | [[Category: Manjunath R]] | ||
| + | [[Category: Prestegard JR]] | ||
| + | [[Category: Valero-Gonzalez J]] | ||
| + | [[Category: Woods RJ]] | ||
Current revision
Crystal structure of the O-fucosylated form of TSRs1-3 from the human thrombospondin 1
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