7q0m
From Proteopedia
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==Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A== | ==Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A== | ||
| - | <StructureSection load='7q0m' size='340' side='right'caption='[[7q0m]]' scene=''> | + | <StructureSection load='7q0m' size='340' side='right'caption='[[7q0m]], [[Resolution|resolution]] 2.54Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q0M FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7q0m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica_subsp._palearctica_YE-P4 Yersinia enterocolitica subsp. palearctica YE-P4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q0M FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q0m OCA], [https://pdbe.org/7q0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q0m RCSB], [https://www.ebi.ac.uk/pdbsum/7q0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q0m ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OPK:(2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic+acid'>OPK</scene>, <scene name='pdbligand=UMQ:UNDECYL-MALTOSIDE'>UMQ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q0m OCA], [https://pdbe.org/7q0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q0m RCSB], [https://www.ebi.ac.uk/pdbsum/7q0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q0m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PEPT_YERP4 PEPT_YERP4] Mediates the proton-dependent uptake of dipeptides. Shows higher affinity for dipeptides with a negatively charged amino acid residue at the N-terminal position, such as Asp-Ala and Glu-Ala. Also displays specificity for Ala-Ala, Ala-Tyr and Tyr-Ala.<ref>PMID:26246134</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Yersinia enterocolitica subsp. palearctica YE-P4]] | ||
[[Category: Fotiadis D]] | [[Category: Fotiadis D]] | ||
[[Category: Ilgue H]] | [[Category: Ilgue H]] | ||
[[Category: Jeckelmann JM]] | [[Category: Jeckelmann JM]] | ||
[[Category: Stauffer M]] | [[Category: Stauffer M]] | ||
Current revision
Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A
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