3gix

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Current revision (07:06, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3gix' size='340' side='right'caption='[[3gix]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
<StructureSection load='3gix' size='340' side='right'caption='[[3gix]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3gix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GIX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3gix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GIX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xbs|1xbs]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIM2, DLP, TXNL4B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gix OCA], [https://pdbe.org/3gix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gix RCSB], [https://www.ebi.ac.uk/pdbsum/3gix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gix ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gix OCA], [https://pdbe.org/3gix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gix RCSB], [https://www.ebi.ac.uk/pdbsum/3gix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gix ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TXN4B_HUMAN TXN4B_HUMAN]] Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.<ref>PMID:15161931</ref>
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[https://www.uniprot.org/uniprot/TXN4B_HUMAN TXN4B_HUMAN] Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.<ref>PMID:15161931</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Guo, F]]
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[[Category: Guo F]]
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[[Category: Jin, T C]]
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[[Category: Jin TC]]
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[[Category: Zhang, Y Z]]
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[[Category: Zhang YZ]]
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[[Category: Cell cycle]]
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[[Category: Dlp]]
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[[Category: Mrna processing]]
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[[Category: Mrna splicing]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Pre-mrna splicing]]
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[[Category: Splicing]]
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[[Category: Txnl4b]]
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Current revision

Crystal structure of human splicing factor dim2

PDB ID 3gix

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