User:Anna Pressel/Sandbox1

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=''Vitamin K Epoxide Reductase''=
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<StructureSection load='6wv4' size='350' frame='true' side='right' caption='VKOR 6wv4' scene='<Vkor_with_cap_domain/1'>VKOR Cap Domain</scene>'>
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<StructureSection load='6wv4' size='350' frame='true' side='right' caption='VKOR 6wv4' scene=''>
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This is a default text for your page '''Anna Pressel/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
This is a default text for your page '''Anna Pressel/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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[[Image:VKOR_Open_Conformation.png|400px|right|thumb|Figure 1]]
[[Image:VKOR_Open_Conformation.png|400px|right|thumb|Figure 1]]
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<ref name="Liu">PMID:33154105</ref>
== Function ==
== Function ==
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<ref name="Ransey">PMID:28504306</ref>
[https://proteopedia.org/wiki/index.php/6wvi VKOR Pufferfish Model]
[https://proteopedia.org/wiki/index.php/6wvi VKOR Pufferfish Model]
== Disease ==
== Disease ==
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== Structural highlights ==
== Structural highlights ==
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<scene name='90/905590/Vkor_with_cap_domain/1'>VKOR Cap Domain</scene>=''Vitamin K Epoxide Reductase''=
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Current revision

VKOR 6wv4

Drag the structure with the mouse to rotate

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Liu S, Li S, Shen G, Sukumar N, Krezel AM, Li W. Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science. 2020 Nov 5. pii: science.abc5667. doi: 10.1126/science.abc5667. PMID:33154105 doi:http://dx.doi.org/10.1126/science.abc5667
  4. Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

  • Anna Pressel
  • George Pappadeas

Proteopedia Page Contributors and Editors (what is this?)

Anna Pressel

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