This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7z5k
From Proteopedia
(Difference between revisions)
m (Protected "7z5k" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Transcription factor MYF5 bound to non-symmetrical site== | |
| - | + | <StructureSection load='7z5k' size='340' side='right'caption='[[7z5k]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7z5k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z5K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z5k OCA], [https://pdbe.org/7z5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z5k RCSB], [https://www.ebi.ac.uk/pdbsum/7z5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z5k ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Taipale | + | [https://www.uniprot.org/uniprot/MYF5_HUMAN MYF5_HUMAN] The disease is caused by variants affecting the gene represented in this entry. |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MYF5_HUMAN MYF5_HUMAN] Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:29887215). Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.<ref>PMID:2721498</ref> <ref>PMID:29887215</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Morgunova E]] | ||
| + | [[Category: Popov A]] | ||
| + | [[Category: Taipale J]] | ||
| + | [[Category: Yin Y]] | ||
Current revision
Transcription factor MYF5 bound to non-symmetrical site
| |||||||||||
