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7rw4

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Current revision (10:42, 22 May 2024) (edit) (undo)
 
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<StructureSection load='7rw4' size='340' side='right'caption='[[7rw4]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
<StructureSection load='7rw4' size='340' side='right'caption='[[7rw4]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7rw4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RW4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7rw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RW4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rw4 OCA], [https://pdbe.org/7rw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rw4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rw4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rw4 OCA], [https://pdbe.org/7rw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rw4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rw4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/JPH1_HUMAN JPH1_HUMAN]] Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
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[https://www.uniprot.org/uniprot/JPH1_HUMAN JPH1_HUMAN] Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Panwar, P]]
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[[Category: Panwar P]]
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[[Category: Petegem, F Van]]
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[[Category: Van Petegem F]]
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[[Category: Yang, Z]]
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[[Category: Yang Z]]
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[[Category: Ion channel]]
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[[Category: Membrane]]
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[[Category: Muscle]]
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[[Category: Structural protein]]
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Current revision

Crystal structure of junctophilin-1

PDB ID 7rw4

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