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7xad

From Proteopedia

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m (Protected "7xad" [edit=sysop:move=sysop])
Current revision (17:50, 29 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7xad is ON HOLD
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==Crystal strucutre of PD-L1 and DBL2_02 designed protein binder==
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<StructureSection load='7xad' size='340' side='right'caption='[[7xad]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xad]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Chemical_production_metagenome Chemical production metagenome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XAD FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xad OCA], [https://pdbe.org/7xad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xad RCSB], [https://www.ebi.ac.uk/pdbsum/7xad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xad ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Chemical production metagenome]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chai Y]]
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[[Category: Gao GF]]
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[[Category: Han P]]
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[[Category: Liu KF]]
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[[Category: Pacesa M]]
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[[Category: Tan SG]]
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[[Category: Xu ZP]]

Current revision

Crystal strucutre of PD-L1 and DBL2_02 designed protein binder

PDB ID 7xad

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OCA

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