7z8u
From Proteopedia
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==Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP== | ==Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP== | ||
| - | <StructureSection load='7z8u' size='340' side='right'caption='[[7z8u]]' scene=''> | + | <StructureSection load='7z8u' size='340' side='right'caption='[[7z8u]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z8U FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7z8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psychrobacter_arcticus Psychrobacter arcticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z8U FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z8u OCA], [https://pdbe.org/7z8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z8u RCSB], [https://www.ebi.ac.uk/pdbsum/7z8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z8u ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z8u OCA], [https://pdbe.org/7z8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z8u RCSB], [https://www.ebi.ac.uk/pdbsum/7z8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z8u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HIS1_PSYA2 HIS1_PSYA2] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[ATP phosphoribosyl transferase 3D structures|ATP phosphoribosyl transferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Psychrobacter arcticus]] | ||
[[Category: Alphey MS]] | [[Category: Alphey MS]] | ||
[[Category: Fisher G]] | [[Category: Fisher G]] | ||
[[Category: Da Silva RG]] | [[Category: Da Silva RG]] | ||
Current revision
Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP
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