6rwn

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Current revision (08:52, 14 July 2024) (edit) (undo)
 
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<SX load='6rwn' size='340' side='right' viewer='molstar' caption='[[6rwn]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<SX load='6rwn' size='340' side='right' viewer='molstar' caption='[[6rwn]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6rwn]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/Civ Civ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RWN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6rwn]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Simian_immunodeficiency_virus Simian immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RWN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DLU:(4R,12AS)-N-(2,4-DIFLUOROBENZYL)-7-HYDROXY-4-METHYL-6,8-DIOXO-3,4,6,8,12,12A-HEXAHYDRO-2H-PYRIDO[1,2 4,5]PYRAZINO[2,1-B][1,3]OXAZINE-9-CARBOXAMIDE'>DLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11723 CIV])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DLU:(4R,12AS)-N-(2,4-DIFLUOROBENZYL)-7-HYDROXY-4-METHYL-6,8-DIOXO-3,4,6,8,12,12A-HEXAHYDRO-2H-PYRIDO[1,2 4,5]PYRAZINO[2,1-B][1,3]OXAZINE-9-CARBOXAMIDE'>DLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwn OCA], [https://pdbe.org/6rwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rwn RCSB], [https://www.ebi.ac.uk/pdbsum/6rwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwn OCA], [https://pdbe.org/6rwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rwn RCSB], [https://www.ebi.ac.uk/pdbsum/6rwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E1ANT8_SIV E1ANT8_SIV]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
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[[Category: Civ]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cherepanov, P]]
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[[Category: Simian immunodeficiency virus]]
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[[Category: Cook, N]]
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[[Category: Cherepanov P]]
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[[Category: Nans, A]]
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[[Category: Cook N]]
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[[Category: Lentivirus]]
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[[Category: Nans A]]
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[[Category: Protein-dna complex]]
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[[Category: Recombination]]
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[[Category: Retroviral integrase]]
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[[Category: Strand transfer inhibior]]
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Current revision

SIVrcm intasome in complex with dolutegravir

6rwn, resolution 3.10Å

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OCA

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