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2vz0

From Proteopedia

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Current revision (15:38, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2vz0' size='340' side='right'caption='[[2vz0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2vz0' size='340' side='right'caption='[[2vz0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vz0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VZ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vz0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VZ0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D64:6-(4-METHYLPHENYL)QUINAZOLINE-2,4-DIAMINE'>D64</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2c7v|2c7v]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D64:6-(4-METHYLPHENYL)QUINAZOLINE-2,4-DIAMINE'>D64</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pteridine_reductase Pteridine reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.33 1.5.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz0 OCA], [https://pdbe.org/2vz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vz0 RCSB], [https://www.ebi.ac.uk/pdbsum/2vz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz0 OCA], [https://pdbe.org/2vz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vz0 RCSB], [https://www.ebi.ac.uk/pdbsum/2vz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O76290_TRYBB O76290_TRYBB]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pteridine reductase]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Trybb]]
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[[Category: Fairlamb AH]]
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[[Category: Fairlamb, A H]]
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[[Category: Robinson DA]]
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[[Category: Robinson, D A]]
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[[Category: Sienkiewicz N]]
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[[Category: Sienkiewicz, N]]
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[[Category: Thompson S]]
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[[Category: Thompson, S]]
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[[Category: Oxidoreductase]]
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[[Category: Short-chain dehydrogenase/reductase]]
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[[Category: Trypanosomatid]]
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Current revision

Pteridine Reductase 1 (PTR1) from Trypanosoma Brucei in complex with NADP and DDD00066641

PDB ID 2vz0

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OCA

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