7dv5
From Proteopedia
(Difference between revisions)
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<StructureSection load='7dv5' size='340' side='right'caption='[[7dv5]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='7dv5' size='340' side='right'caption='[[7dv5]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DV5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TCH:TAUROCHOLIC+ACID'>TCH</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TCH:TAUROCHOLIC+ACID'>TCH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dv5 OCA], [https://pdbe.org/7dv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dv5 RCSB], [https://www.ebi.ac.uk/pdbsum/7dv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dv5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dv5 OCA], [https://pdbe.org/7dv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dv5 RCSB], [https://www.ebi.ac.uk/pdbsum/7dv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dv5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [[https://www.uniprot.org/uniprot/ABCBB_HUMAN ABCBB_HUMAN]] Progressive familial intrahepatic cholestasis type 2;Intrahepatic cholestasis of pregnancy;Benign recurrent intrahepatic cholestasis type 2. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| - | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/ABCBB_HUMAN ABCBB_HUMAN]] Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner (PubMed:16332456). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456).<ref>PMID:16332456</ref> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen | + | [[Category: Chen Y]] |
| - | [[Category: How | + | [[Category: How WT]] |
| - | [[Category: Wang | + | [[Category: Wang L]] |
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Current revision
Human bile salt exporter ABCB11 in complex with taurocholate
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Categories: Large Structures | Chen Y | How WT | Wang L
