2z2c
From Proteopedia
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<StructureSection load='2z2c' size='340' side='right'caption='[[2z2c]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='2z2c' size='340' side='right'caption='[[2z2c]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2z2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2z2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z2C FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=UDC:2-(ACETYLAMINO)-3-O-[(2S,3S)-2-CARBOXY-3,4-DIHYDROXYBUTAN-2-YL]-2-DEOXY-ALPHA-D-GLUCOPYRANOSE'>UDC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2c OCA], [https://pdbe.org/2z2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2c RCSB], [https://www.ebi.ac.uk/pdbsum/2z2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2c ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2c OCA], [https://pdbe.org/2z2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2c RCSB], [https://www.ebi.ac.uk/pdbsum/2z2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2c_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2c_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Klein CD]] | |
| - | [[Category: Klein | + | [[Category: Scheidig AJ]] |
| - | [[Category: Scheidig | + | [[Category: Skarzynski T]] |
| - | [[Category: Skarzynski | + | [[Category: Steinbach A]] |
| - | [[Category: Steinbach | + | |
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Current revision
MURA inhibited by unag-cnicin adduct
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