Copy1
From Proteopedia
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| - | <StructureSection load='1klc' size='340' side='right' scene='' caption=' | + | <StructureSection load='1klc' size='340' side='right' scene='' caption='Human transforming growth factor-beta 1 (PDB code 1klc)'> |
The TGFbeta signalling pathway has an impact on a variety of cellular processes including cell proliferation, differentiation, apoptosis, growth, development, adhesion, neuronal growth, immune surveillance, tissue homeostasis and many others. Moreover, dysregulation of the normal functioning of any element is associated with pathological conditions, such as autoimmune and inflammatory diseases, cancer and cardiovascular diseases. | The TGFbeta signalling pathway has an impact on a variety of cellular processes including cell proliferation, differentiation, apoptosis, growth, development, adhesion, neuronal growth, immune surveillance, tissue homeostasis and many others. Moreover, dysregulation of the normal functioning of any element is associated with pathological conditions, such as autoimmune and inflammatory diseases, cancer and cardiovascular diseases. | ||
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<scene name='41/416407/Dimer_tgf_beta/1'>TgF beta dimer</scene> | <scene name='41/416407/Dimer_tgf_beta/1'>TgF beta dimer</scene> | ||
| - | =='''TGFβ receptors'''== | ||
| - | ===''' TGFβ receptor ectodomain'''=== | ||
| - | ===''' TGFβ receptor endodomain'''=== | ||
| - | ==''' TGFβ signalling'''== | ||
| - | ===''' Latent TGFβ structure and activation'''=== | ||
| - | ==== '''pro-TGFβ-1 processing '''==== | ||
| - | ===''' TGFβ-1:TβRII:TβRI ternary complex '''=== | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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