Nodal signaling pathway
From Proteopedia
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(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> The Nodal family of proteins, ...) |
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| - | + | <StructureSection load='4n1d' size='340' side='right' caption='Nodal/BMP2 chimera NB250 (PDB code [[4n1d]])' scene='90/909304/Cv/1'> | |
| - | <StructureSection load=' | + | The Nodal signaling pathway is a signal transduction pathway important in regional and cellular differentiation during embryonic development. The Nodal family of proteins, a subset of the [[TGF beta signaling pathway#The TGF beta superfamily of ligands|transforming growth factor beta (TGFβ) superfamily]], is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral axis in vertebrate embryos. Activation of the Nodal pathway involves nodal binding to activin and activin-like receptors which leads to phosphorylation of the Smad2. |
| - | The Nodal family of proteins, a subset of the transforming growth factor beta (TGFβ) superfamily, is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral axis in vertebrate embryos. Activation of the Nodal pathway involves nodal binding to activin and activin-like receptors which leads to phosphorylation of the Smad2. | + | |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
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