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7zgo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human NKCC1 (TM domain)== | |
| - | + | <StructureSection load='7zgo' size='340' side='right'caption='[[7zgo]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zgo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZGO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zgo OCA], [https://pdbe.org/7zgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zgo RCSB], [https://www.ebi.ac.uk/pdbsum/7zgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zgo ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Habeck | + | [https://www.uniprot.org/uniprot/S12A2_HUMAN S12A2_HUMAN] Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Lindorff-Larsen | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fenton R]] |
| - | [[Category: | + | [[Category: Gad H]] |
| - | [[Category: | + | [[Category: Habeck M]] |
| - | [[Category: | + | [[Category: Hartmann R]] |
| - | [[Category: | + | [[Category: Kock Flygaard R]] |
| + | [[Category: Lindorff-Larsen K]] | ||
| + | [[Category: Lindtoft Rosenbaek L]] | ||
| + | [[Category: Lykkegaard Karlsen J]] | ||
| + | [[Category: Lyons J]] | ||
| + | [[Category: Neumann C]] | ||
| + | [[Category: Nissen P]] | ||
| + | [[Category: Wang Y]] | ||
Current revision
Cryo-EM structure of human NKCC1 (TM domain)
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