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7tmr
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| - | ==== | + | ==V-ATPase from Saccharomyces cerevisiae, State 1== |
| - | <StructureSection load='7tmr' size='340' side='right'caption='[[7tmr]]' scene=''> | + | <StructureSection load='7tmr' size='340' side='right'caption='[[7tmr]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7tmr]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TMR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tmr OCA], [https://pdbe.org/7tmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tmr RCSB], [https://www.ebi.ac.uk/pdbsum/7tmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tmr ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tmr OCA], [https://pdbe.org/7tmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tmr RCSB], [https://www.ebi.ac.uk/pdbsum/7tmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tmr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VATA_YEAST VATA_YEAST] Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase (vacuolar ATPase) is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mV, inside positive and acidic, in the vacuolar membrane vesicles. It may participate in maintenance of cytoplasmic Ca(2+) homeostasis. This is a catalytic subunit.<ref>PMID:1534148</ref> PI-SceI is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates "homing", a genetic event that converts a VMA1 allele lacking VDE into one that contains it.<ref>PMID:1534148</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[ATPase 3D structures|ATPase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae]] |
| + | [[Category: Bueler SA]] | ||
| + | [[Category: Jaskolka MC]] | ||
| + | [[Category: Keon KA]] | ||
| + | [[Category: Rubinstein JL]] | ||
| + | [[Category: Vasanthakumar T]] | ||
Current revision
V-ATPase from Saccharomyces cerevisiae, State 1
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