5jwt

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Current revision (09:49, 27 September 2023) (edit) (undo)
 
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<StructureSection load='5jwt' size='340' side='right'caption='[[5jwt]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='5jwt' size='340' side='right'caption='[[5jwt]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5jwu|5jwu]], [[5jwv|5jwv]], [[5jww|5jww]], [[5jwx|5jwx]], [[5jws|5jws]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwt OCA], [https://pdbe.org/5jwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwt RCSB], [https://www.ebi.ac.uk/pdbsum/5jwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwt OCA], [https://pdbe.org/5jwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwt RCSB], [https://www.ebi.ac.uk/pdbsum/5jwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Lysin|Lysin]]
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*[[Lysin 3D structures|Lysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt4]]
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[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Fischer M]]
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[[Category: Fischer, M]]
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[[Category: Lee H]]
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[[Category: Lee, H]]
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[[Category: Liu S-Y]]
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[[Category: Liu, S Y]]
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[[Category: Shoichet BK]]
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[[Category: Shoichet, B K]]
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[[Category: Hydrolase]]
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[[Category: Phage lysozyme azaborine]]
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Current revision

T4 Lysozyme L99A/M102Q with Benzene Bound

PDB ID 5jwt

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OCA

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