2x79
From Proteopedia
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<StructureSection load='2x79' size='340' side='right'caption='[[2x79]], [[Resolution|resolution]] 3.80Å' scene=''> | <StructureSection load='2x79' size='340' side='right'caption='[[2x79]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2x79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2x79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Microbacterium_liquefaciens Microbacterium liquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X79 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x79 OCA], [https://pdbe.org/2x79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x79 RCSB], [https://www.ebi.ac.uk/pdbsum/2x79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x79 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x79 OCA], [https://pdbe.org/2x79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x79 RCSB], [https://www.ebi.ac.uk/pdbsum/2x79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x79 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/HYUP_MICLQ HYUP_MICLQ] Nucleobase-proton symporter that mediates the sodium-dependent binding and uptake of 5-aryl-substituted hydantoin compounds (PubMed:16621827, PubMed:24952894). 5-indolyl methyl hydantoin and 5-benzyl hydantoin are the preferred substrates, with selectivity for a hydrophobic substituent in position 5 of hydantoin and for the L isomer over the D isomer (PubMed:16621827, PubMed:24952894).<ref>PMID:16621827</ref> <ref>PMID:24952894</ref> <ref>PMID:16116274</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x7/2x79_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x7/2x79_consurf.spt"</scriptWhenChecked> | ||
- | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Microbacterium liquefaciens orla-jensen 1919]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Beckstein | + | [[Category: Microbacterium liquefaciens]] |
- | [[Category: Cameron | + | [[Category: Beckstein O]] |
- | [[Category: Hadden | + | [[Category: Cameron AD]] |
- | [[Category: Henderson | + | [[Category: Hadden JM]] |
- | [[Category: Iwata | + | [[Category: Henderson PJF]] |
- | [[Category: Rutherford | + | [[Category: Iwata S]] |
- | [[Category: Sansom | + | [[Category: Rutherford NG]] |
- | [[Category: Sharples | + | [[Category: Sansom MSP]] |
- | [[Category: Shimamura | + | [[Category: Sharples D]] |
- | [[Category: Weyand | + | [[Category: Shimamura T]] |
- | + | [[Category: Weyand S]] | |
- | + | ||
- | + |
Current revision
Inward facing conformation of Mhp1
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