Tailspike protein

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The C-terminal domain (CTD) (residues 109-end) of TSP is responsible for the attachment of the tailspike protein to the O-antigen moiety on bacterial cell surface. The 3D structure of an <scene name='84/841073/Cv/3'>octasaccharide</scene> bound to CTP of TSP shows <scene name='84/841073/Cv/7'>numerous hydrophobic interactions as well as defined water molecules forming hydrogen bonds to the antigen</scene><ref>PMID:23292517</ref>.
The C-terminal domain (CTD) (residues 109-end) of TSP is responsible for the attachment of the tailspike protein to the O-antigen moiety on bacterial cell surface. The 3D structure of an <scene name='84/841073/Cv/3'>octasaccharide</scene> bound to CTP of TSP shows <scene name='84/841073/Cv/7'>numerous hydrophobic interactions as well as defined water molecules forming hydrogen bonds to the antigen</scene><ref>PMID:23292517</ref>.
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</StructureSection>
 
==3D structures of tailspike protein==
==3D structures of tailspike protein==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[Tailspike protein 3D structures]]
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Full size tailspike protein
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**[[2xc1]] - P22TSP - bacteriophage P22<br />
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**[[5w6p]] - CBA120TSP2 - bacteriophage CBA120<br />
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**[[6nw9]], [[5w6f]] - CBA120TSP3<br />
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**[[5js4]] - AB6TSP - bacteriophage PHIAB6<br />
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**[[5jsd]] - AB6TSP + polysaccharide<br />
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**[[4ru5]] - TSP - bacteriophage PHI297<br />
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**[[5jse]] - TSP + polysaccharide - bacteriophage PHIAB6<br />
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**[[4qnl]] - TSP - bacteriophage G7C<br />
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**[[6w4q]], [[7rev]], [[7rfv]], [[7rfo]] – TSP 4 – Escherichia virus<br />
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*Tailspike protein N-terminal NTD 1-108
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**[[1lkt]] - P22TSP NTD<br />
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**[[2vky]] - P22TSP NTD/isoleucine zipper<br />
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**[[2vnl]] - P22TSP NTD/isoleucine zipper (mutant)<br />
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**[[2vji]] - HK620TSP NTD - bacteriophage HK620<br />
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*Tailspike protein C-terminal CTD 109-end
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**[[1tyv]], [[1tyu]], [[1tyx]], [[1tyw]], [[2vfm]], [[1tsp]] - P22TSP CTD <br />
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**[[1qq1]], [[1qrc]], [[1qrb]], [[2vfp]], [[2vfo]], [[2vfq]], [[1qa3]], [[1qa2]], [[1qa1]], [[2vfn]], [[1clw]] - P22TSP CTD (mutant)<br />
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**[[4avz]], [[4xon]], [[4xqf]], [[4xlc]], [[4xl9]], [[4xkv]], [[4xlh]], [[4xnf]], [[4xn0]] - HK520TSP CTD (mutant)<br />
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**[[2vbe]] - TSP CTD - bacteriophage SFVI<br />
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**[[2vbk]] - SF6TSP CTD - bacteriophage SF6<br />
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**[[5w6h]] - CBA120TSP4 active domain 344-1056<br />
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**[[6f7d]], [[6f7k]], [[2v5i]] - SF6TSP CTD - bacteriophage DET7<br />
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**[[6e0v]] - PHI92TSP CTD - bacteriophage PHI92<br />
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**[[6e1r]] - TSP CTD - bacteriophage VB_APIP_P1<br />
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**[[6eu4]] - TSP CTD - bacteriophage VB_ABAP_AS12<br />
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**[[5w5p]] - TSP CTD - bacteriophage AM24<br />
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**[[4ru4]] - TSP CTD - bacteriophage LKA1<br />
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**[[6c72]] - TSP CTD - bacteriophage FRI1<br />
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**[[3gvl]] - KIFTSP CTD - bacteriophage KIF<br />
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**[[3gvj]], [[3gvk]] - KIFTSP CTD (mutant)<br />
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**[[3riq]] - TSP CTD - siphovirus 9NA<br />
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*Tailspike protein CTD complex with polysaccharides
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**[[3th0]] - P22TSP CTD + octasaccharide<br />
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**[[2x85]], [[2vjj]], [[2x6x]], [[6g0x]] - HK520TSP CTD + polysaccharide<br />
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**[[2x6w]], [[2x6y]], [[4xla]], [[5xop]], [[5xor]], [[4xr6]], [[4yej]], [[4yel]], [[4xle]], [[4xlf]], [[4xkw]], [[4xm3]], [[4xmy]], [[4xn3]], [[4xot]], [[6gvp]], [[6gvr]] - HK520TSP CTD (mutant) + polysaccharide<br />
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**[[2vbm]], [[4urr]] - SF6TSP CTD + polysaccharide<br />
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**[[5w6s]] - CBA120TSP4 active domain + polysaccharide<br />
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**[[5w6s]] - CBA120TSP4 active domain + polysaccharide<br />
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**[[6e0w]] - PHI92TSP CTD + colanic acid<br />
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}}
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Glycosylated tailspike protein from bacteriophage P222 complex with octasaccharide (PDB code 3th0)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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