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3iom
From Proteopedia
(Difference between revisions)
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<StructureSection load='3iom' size='340' side='right'caption='[[3iom]], [[Resolution|resolution]] 2.14Å' scene=''> | <StructureSection load='3iom' size='340' side='right'caption='[[3iom]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3iom]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3iom]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IOM FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNG:2-DEOXY-GUANOSINE'>GNG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iom OCA], [https://pdbe.org/3iom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iom RCSB], [https://www.ebi.ac.uk/pdbsum/3iom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iom ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iom OCA], [https://pdbe.org/3iom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iom RCSB], [https://www.ebi.ac.uk/pdbsum/3iom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iom ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PUNA_MYCTU PUNA_MYCTU] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity). | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Purine-nucleoside phosphorylase]] | ||
| - | [[Category: Azevedo, W F.de]] | ||
| - | [[Category: Basso, L A]] | ||
| - | [[Category: Santos, D S]] | ||
| - | [[Category: -deoxyguanosine]] | ||
| - | [[Category: Glycosyltransferase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: | + | [[Category: Basso LA]] |
| - | [[Category: | + | [[Category: Santos DS]] |
| + | [[Category: De Azevedo Jr WF]] | ||
Current revision
Crystal structure of Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis in complex with 2'-Deoxyguanosine
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