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3j31

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<SX load='3j31' size='340' side='right' viewer='molstar' caption='[[3j31]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
<SX load='3j31' size='340' side='right' viewer='molstar' caption='[[3j31]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3j31]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_turreted_icosahedral_virus Sulfolobus turreted icosahedral virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J31 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3j31]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_turreted_icosahedral_virus_1 Sulfolobus turreted icosahedral virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J31 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j31 OCA], [https://pdbe.org/3j31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j31 RCSB], [https://www.ebi.ac.uk/pdbsum/3j31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j31 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j31 OCA], [https://pdbe.org/3j31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j31 RCSB], [https://www.ebi.ac.uk/pdbsum/3j31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j31 ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q6Q0L4_9VIRU Q6Q0L4_9VIRU]
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Sulfolobus turreted icosahedral virus (STIV) was isolated in acidic hot springs where it infects the archeon Sulfolobus solfataricus. We determined the STIV structure using near-atomic resolution electron microscopy and X-ray crystallography allowing tracing of structural polypeptide chains and visualization of transmembrane proteins embedded in the viral membrane. We propose that the vertex complexes orchestrate virion assembly by coordinating interactions of the membrane and various protein components involved. STIV shares the same coat subunit and penton base protein folds as some eukaryotic and bacterial viruses, suggesting that they derive from a common ancestor predating the divergence of the three kingdoms of life. One architectural motif (beta-jelly roll fold) forms virtually the entire capsid (distributed in three different gene products), indicating that a single ancestral protein module may have been at the origin of its evolution.
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Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography.,Veesler D, Ng TS, Sendamarai AK, Eilers BJ, Lawrence CM, Lok SM, Young MJ, Johnson JE, Fu CY Proc Natl Acad Sci U S A. 2013 Mar 21. PMID:23520050<ref>PMID:23520050</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3j31" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</SX>
</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Sulfolobus turreted icosahedral virus]]
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[[Category: Sulfolobus turreted icosahedral virus 1]]
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[[Category: Eilers, B J]]
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[[Category: Eilers BJ]]
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[[Category: Fu, C Y]]
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[[Category: Fu C-Y]]
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[[Category: Johnson, J E]]
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[[Category: Johnson JE]]
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[[Category: Lawrence, C M]]
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[[Category: Lawrence CM]]
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[[Category: Lok, S M]]
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[[Category: Lok SM]]
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[[Category: Ng, T S]]
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[[Category: Ng TS]]
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[[Category: Sendamarai, A K]]
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[[Category: Sendamarai AK]]
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[[Category: Veesler, D]]
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[[Category: Veesler D]]
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[[Category: Young, M J]]
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[[Category: Young MJ]]
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[[Category: Archaea]]
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[[Category: Evolution]]
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[[Category: Virus]]
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[[Category: Virus assembly]]
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Current revision

Life in the extremes: atomic structure of Sulfolobus Turreted Icosahedral Virus

3j31, resolution 4.50Å

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