Thrombin 3D Structures

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3D Structures of thrombin

Updated on 19-August-2024 - For a general description of the protein see Thrombin

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Thrombin_3D_Structures"

Category: Topic Page

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 *'''Thrombin'''
-**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />
+**[[3gic]], [[3r3g]] - hThr HC + LC - human<br />
-**[[3jz1]], [[3jz2]], [[2od3]], [[6pxq]], [[6pxj]] - hThr HC + LC (mutant) <br />
+**[[2od3]], [[3jz1]], [[3jz2]], [[6pxj]], [[6pxq]] - hThr HC + LC (mutant) <br />
 **[[7sr9]] - hThr HC (mutant) + LC (mutant)<br />
-**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />
+**[[1jou]], [[1sg8]], [[1sgi]], [[2a0q]], [[3ee0]], [[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], - hThr HC (mutant) + LC<br />
 **[[2hnt]]– hThr-γ HC + LC<br />
 **[[3pmb]] - bThr HC + LC – bovine<br />
@@ Line 17: / Line 17: @@
 *Thrombin complexes with small molecule
-**[[1bhx]], [[1abj]], [[1ppb]] - hThr HC + LC + inhibitor<br />
+**[[1abj]], [[1bhx]], [[1ppb]], [[6z48]], [[8ase]] - hThr HC + LC + inhibitor<br />
 **[[4rn6]] - hThr HC (mutant) + inhibitor<br />
 **[[3dd2]] - hThr HC + LC + RNA<br />
-**[[1hao]], [[1hap]], [[1hut]] - hThr HC + LC + DNA<br />
+**[[1hao]], [[1hap]], [[1hut]], [[3qlp]], [[4dih]], [[4lz1]], 4lz4]], [[6z8w]], [[6z8x]], [[7ntu]], [[7zkl]], [[7zkm]], [[7zkn]], [[7zko]], [[8bw5]] - hThr HC + LC + aptamer<br />
 **[[3bf6]] - hThr HC + LC + suramin<br />
 **[[1xmn]] - hThr HC + LC + heparin<br />
 **[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />
 **[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
-**[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
+**[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[2pgq]],[[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
 **[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />
+**[[6gwe]], [[6t7h]] - hThr HC + LC + macrocycle<br />
+**[[5cmx]], [[5ew1]], [[5ew2]] - hThr HC + LC + DNA<br />
+**[[5do4]] - hThr HC + LC + RNA<br />
 **[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
 **[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
@@ Line 39: / Line 42: @@
 **[[1fph]] - hThr HC + LC + fibrinogen peptide<br />
 **[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br />
-**[[2a2x]], [[1eb1]], [[1h8i]], [[1h8d]], [[1dit]], [[1hbt]], [[3u8t]] - hThr HC + LC + peptide inhibitor<br />
+**[[1dlt]], [[1eb1]], [[1h8d]], [[1h8i]], [[1hbt]], [[2a2x]], [[3u8t]] - hThr HC + LC + peptide inhibitor<br />
-**[[1g37]], [[1eoj]], [[1eol]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
+**[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
 **[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />
+**[[3qdz]] - hThr HC (mutant) + LC + PAR4 peptide<br />
 **[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />
 **[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />
 **[[1dlk]] - bThr HC + LC + peptide inhibitor<br />
-**[[1ycp]], [[1bbr]] – bThr-ε HC + LC + fibrinogen peptide<br />
+**[[1bbr]], [[1ycp]] – bThr-ε HC + LC + fibrinogen peptide<br />
 **[[1ucy]] - bThr HC + LC + fibrinogen peptide<br />
 **[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />
@@ Line 54: / Line 58: @@
 *Thrombin complexes containing hirudin
-**[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[6eo8]], [[6eo9]], [[4loy]] - hThr HC + LC + hirudin peptide + inhibitor<br />
+**[[1a3b]], [[1a3e]], [[1ype]], [[1a46]], [[1a4w]], [[1a5g]], [[1a61]], [[1ad8]], [[1ae8]], [[1afe]], [[1aht]], [[1ai8]], [[1aix]], [[1awf]], [[1awh]], [[1ay6]], [[1b5g]], [[1ba8]], [[1bb0]], [[1bcu]], [[1bmm]], [[1bmn]], [[1c1u]], [[1c1v]], [[1c1w]], [[1c4u]], [[1c4v]], [[1c4y]], [[1c5n]], [[1c5o]], [[1ca8]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1d4p]], [[1fpc]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1qj1]], [[1gj4]], [[1gj5]], [[1qj6]], [[1qj7]], [[1kts]], [[1ktt]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1o2g]], [[1oyt]], ,[[1qhr]], [[1qur]], [[1riw]], [[1tbz]], [[1uma]], [[1vzq]], [[1w7g]], [[1way]], [[1wbg]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]],  [[2anm]], [[2bdy]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bxt]], [[2bxu]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2feq]], [[2fes]], [[2gde]], [[2jh0]], [[2jh5]], [[2jh6]], [[2pks]], [[2r2m]], [[2uuj]], [[2uuk]], [[2v3h]], [[2v3o]], [[2w7g]], [[2zc9]], [[2zda]], [[2zdv]], [[2zf0]], [[2zff]], [[2zfp]], [[2zfq]], [[2zfr]], [[2zg0]], [[2zgb]], [[2zgx]], [[2zhe]], [[2zhf]], [[2zhq]], [[2zhw]], [[2zi2]], [[2ziq]], [[[2znk]], [2zo3]], [[3biu]], [[3biv]], [[3c27]], [[3d49]], [[3da9]], [[3dhk]], [[3dt0]], [[3dux]], [[3egk]], [[3eq0]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3sv2]], [[3t5f]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[4loy]], [[6eo8]], [[6eo9]], [[6gbw]], [[6zgo]] - hThr HC + LC + hirudin peptide + inhibitor<br />
-**[[7kme]] – hThr-a HC + LC + hirudin peptide + protein inhibitor<br />
 **[[7ac9]] – hThr HC + LC + hirudin peptide + Arg<br />
-**[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[4baq]], [[4bao]], [[4ban]], [[4bak]], [[4bam]], [[4bah]], [[5lpd]], [[5ahg]], [[5afz]], [[5afy]], [[5af9]], [[5a2m]], [[4yes]], [[4ufg]], [[4uff]], [[4ufe]], [[4ufd]], [[4ueh]], [[4ue7]], [[4udw]], [[4ud9]] - hThr HC + hirudin peptide + inhibitor<br />
+**[[1d6w]], [[1d9i]], [[1doj]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[1qbv]], [[1tmu]], [[1nm6]], [[1nt1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1xm1]], [[1z71]], [[1zgi]], [[1zgv]], [[1zrb]], [[4baq]], [[4bao]], [[4ban]], [[4ud9]], [[4udw]], [[4ue7]], [[4ueh]], [[4ufd]], [[4ufe]], [[4uff]], [[4ufg]], [[4yes]], [[5a2m]], [[5af9]],  - hThr HC + hirudin peptide + inhibitor<br />
-**[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
+**[[1a2c]], [[1hdt]], [[1ny2]], [[1tmt]], [[1tmb]], [[1tom]], [[3u8o]], [[3u8r]], [[7kme]], [[8kme]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
 **[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br />
-**[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]], [[3htc]], [[4htc]]  - hThr HC + LC + hirudin peptide<br />
+**[[1abi]], [[1c5l]], [[1hgt]], [[1hxe]], [[1hxf]], [[1ihs]], [[1iht]], [[1no9]], [[1thr]], [[1ths]], [[1vr1]], [[2hgt]], [[2pw8]], [[2uuf]], [[3htc]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]], [[4htc]], [[4thn]], [[5gds]] - hThr HC + LC + hirudin peptide<br />
 **[[3vxe]], [[3vxf]] - hThr HC + LC + bivalirudin peptide<br />
 **[[4mlf]] - hThr HC (mutant) + LC + hirudin peptide<br />
-**[[5mm6]], [[5mls]], [[5mjt]] - hThr HC (mutant) + LC + hirudin peptide + inhibitor<br />
+**[[5mls]], [[5mjt]], [[5mm6]] - hThr HC (mutant) + LC + hirudin peptide + inhibitor<br />
-**[[1vit]], [[1hrt]] - bThr HC + LC + hirudin peptide<br />
+**[[1hrt]], [[1vit]] - bThr HC + LC + hirudin peptide<br />
 *Thrombin complex with protein
@@ Line 83: / Line 86: @@
 **[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
 **[[3b23]] - hThr HC + LC + variegin<br />
-**[[6tkj]], [[6tki]], [[6tkh]] - hThr HC + LC + tsetse Thr inhibitor<br />
+**[[1id5]] - hThr HC + LC + ecotin<br />
+**[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br />
 **[[5e8e]] - hThr HC + LC + antibody<br />
-**[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase<br />
+**[[1nu7]], [[2a1d]] – bThr HC + LC + staphylocoagulase<br />
 **[[1avg]] - bThr HC + LC + triabin<br />
 **[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI<br />
@@ Line 93: / Line 97: @@
 *'''Prothrombin'''
-**[[3e6p]], [[2afq]], [[3u69]], [[6v5t]] - hPThr HC + LC<br />
+**[[2afq]], [[3u69]] - hPThr HC + LC<br />
 **[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />
-**[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]], [[4hzh]], [[4h6t]], [[4h6s]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
+**[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
 **[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) <br />
-**[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156
+**[[1nl1]], [[1nl2]], [[2pf1]], [[2pf2]], [[2spt]] – bPThr residues 1-156
 *Prothrombin complexes
 **[[6cym]] - hPThr HC + LC + inhibitor<br />
-**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
+**[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
-**[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
 **[[1sr5]] - hPThr HC + LC + antithrombin III<br />
-**[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
 **[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
 **[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />
 **[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />
-**[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
+**[[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
-**[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br />
+**[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]]  [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]],  [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
-**[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]], [[1o5g]], [[3tu7]], [[4lxb]], [[5lce]], [[6tdt]], [[6eo9]], [[6eo8]], [[6zun]], [[6zuh]], [[6zug]], [[6zv7]], [[6zuu]], [[6zux]], [[6zuw]], [[6zv8]], [[6i51]], [[6t3q]], [[6t4a]], [[6hsx]], [[6t3m]], [[6t52]], [[6t57]], [[6t89]], [[6t8a]], [[6fjt]], [[6t54]], [[6t53]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
 **[[4ax9]] - hPThr HC + LC + hirudin peptide<br />
 **[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
 **[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
-**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]], [[6eo7]], [[6eo6]], [[6gn7]], [[6evv]] - hPThr HC + LC + DNA<br />
+**[[4dii]], [[4i7y]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + DNA aptamer<br />
-**[[5do4]] - hPThr HC + LC + RNA<br />
+**[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />
-**[[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />
 *Prothrombin complex with protein
-**[[1id5]] - hPThr HC + LC + ecotin<br />
 **[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />
 **[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />
@@ Line 130: / Line 129: @@
 **[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />
-*'''Prethrombin-1'''
+*'''Prethrombin-1 residues 199-622'''
-**[[3nxp]] - hThr residues 199-622
+**[[3nxp]] - hThr
-*'''Prethrombin-2'''
+*'''Prethrombin-2 residues 328-622'''
+**[[6v5t]] – hThr<br />
 **[[1nu9]] – hThr + staphylocoagulase<br />
 **[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />
 **[[1hag]], [[1hah]] – hThr + hirudin peptide<br />
 **[[1hai]] – hThr + inhibitor<br />
-**[[3sqe]], [[3sqh]] - hThr (mutant)
+**[[3sqe]], [[3sqh]] - hThr (mutant)<br />
+**[[3k65]] - hThr HC residues 315-622 (mutant) + LC residues 199-314<br />
 *'''Meizothrombin'''
-**[[1a0h]] - bMThr
+**[[3e6p]] – hMthr HC 364-622 + LC 206-363
+**[[1a0h]] – bMThr HC 367-625 + LC 208-366
+*'''Saxthrombin'''
+**[[3s69]] – Thr – Gloydis saxatilis<br />
 }}
 [[Category:Topic Page]]

Thrombin 3D Structures

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3D Structures of thrombin

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