Topoisomerase 3D structures
From Proteopedia
(Difference between revisions)
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**[[1a41]] – VvTOPI C-terminal – Vaccinia virus<br /> | **[[1a41]] – VvTOPI C-terminal – Vaccinia virus<br /> | ||
**[[1vcc]] – VvTOPI N-terminal<br /> | **[[1vcc]] – VvTOPI N-terminal<br /> | ||
| - | **[[5d5h]], [[5uj1]], [[5ujy]] - MtTOPI – ''Mycobacterium tuberculosis''<br /> | + | **[[5d5h]], [[5uj1]], [[5ujy]], [[8tfg]] - MtTOPI – ''Mycobacterium tuberculosis''<br /> |
| - | **[[6cq2]], [[6cqi]] – MtTOPI + DNA<br /> | + | **[[6cq2]], [[6cqi]], [[8czq]] – MtTOPI + DNA<br /> |
**[[3igc]], [[2h7f]], [[2h7g]] – TOPI+DNA – Smallpox virus<br /> | **[[3igc]], [[2h7f]], [[2h7g]] – TOPI+DNA – Smallpox virus<br /> | ||
**[[2gai]], [[2gaj]] – TOPI – ''Thermotoga maritime''<br /> | **[[2gai]], [[2gaj]] – TOPI – ''Thermotoga maritime''<br /> | ||
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**[[6pcm]] – TOPI + DNA – ''Mycolicibacterium smegmatis''<br /> | **[[6pcm]] – TOPI + DNA – ''Mycolicibacterium smegmatis''<br /> | ||
**[[6z01]], [[6z03]] – TOPI – ''Candidatus caldarcheum subterraneum''<br /> | **[[6z01]], [[6z03]] – TOPI – ''Candidatus caldarcheum subterraneum''<br /> | ||
| + | **[[8sjh]], [[8sji]] – TOPI - synthetic<br /> | ||
*Topoisomerase I (ATP-dependent) is reverse gyrase. See [[Gyrase]] | *Topoisomerase I (ATP-dependent) is reverse gyrase. See [[Gyrase]] | ||
| - | *TOPII | + | *Topoisomerase II |
| + | |||
| + | **[[7l6s]] – TOPII ATPase and transducer domain 103-525 - baboon<br /> | ||
| + | **[[6ca8]] – TOPII DNA-binding domain 469-1212 – ''Plasmodium falciparum''<br /> | ||
| + | **[[8j9y]], [[8j9z]] – TOPII – African swine fever virus – Cryo EM<br /> | ||
*Topoisomerase IIA | *Topoisomerase IIA | ||
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**[[1pvg]] – yTOPII N-terminal<br /> | **[[1pvg]] – yTOPII N-terminal<br /> | ||
**[[1bjt]], [[1bgw]] – yTOPII core<br /> | **[[1bjt]], [[1bgw]] – yTOPII core<br /> | ||
| + | **[[8gcc]] – TOPIIA + DNA + inhibitor – ''Trypanosoma cruzi'' – Cryo EM<br /> | ||
*Topoisomerase IIB topo VI | *Topoisomerase IIB topo VI | ||
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**[[5zrf]], [[5zen]], [[5zqf]] - hTOPIIB subunit B + DNA <br /> | **[[5zrf]], [[5zen]], [[5zqf]] - hTOPIIB subunit B + DNA <br /> | ||
**[[4g0w]], [[3qx3]], [[4g0v]], [[4g0u]], [[5gwj]], [[5gwi]] - hTOPIIB + DNA + anti-cancer drug<br /> | **[[4g0w]], [[3qx3]], [[4g0v]], [[4g0u]], [[5gwj]], [[5gwi]] - hTOPIIB + DNA + anti-cancer drug<br /> | ||
| + | **[[7qfn]] - hTOPIIB ATPase domain 50-449 + ADP <br /> | ||
| + | **[[7qfo]] - hTOPIIB ATPase domain + AMPPNP <br /> | ||
| + | **[[7zbg]] - hTOPIIB ATPase domain + ADP + piperazine derivative <br /> | ||
**[[2zbk]] – SsTOPIIB subunit A+B – ''Sulfolobus shibatae''<br /> | **[[2zbk]] – SsTOPIIB subunit A+B – ''Sulfolobus shibatae''<br /> | ||
**[[2hkj]], [[1mu5]], [[1mx0]] - SsTOPIIB subunit B<br /> | **[[2hkj]], [[1mu5]], [[1mx0]] - SsTOPIIB subunit B<br /> | ||
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*Topoisomerase V | *Topoisomerase V | ||
| - | **[[2csb]], [[2csd | + | **[[2csb]], [[2csd]] – MkTOPV 1-519 – ''Methanopyrus kandleri''<br /> |
| - | **[[ | + | **[[5hm5]] - MkTOPV 1-854 <br /> |
| - | **[[3m6z]] - MkTOPV | + | **[[4gfj]] – MkTOPV 1-685<br /> |
| - | **[[3m7d]] - MkTOPV | + | **[[3m6k]] – MkTOPV 1-380<br /> |
| + | **[[3m7g]] – MkTOPV 1-269<br /> | ||
| + | **[[3m6z]] - MkTOPV 1-380 +guanidine<br /> | ||
| + | **[[3m7d]] - MkTOPV 1-380 +dioxane<br /> | ||
| + | **[[3m6z]], [[8df7]], [[8df8]], [[8df9]], [[8dfb]] - MkTOPV (mutant) 1-854 + DNA<br /> | ||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D Structures of Topoisomerase
Updated on 28-December-2023 - For a general description of the protein see Topoisomerase
