Transaldolase
From Proteopedia
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== Function == | == Function == | ||
'''Transaldolase''' (TAL) is part of the pentose phosphate pathway. It catalyzes the transformation of sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate<ref>PMID:15960612</ref>. | '''Transaldolase''' (TAL) is part of the pentose phosphate pathway. It catalyzes the transformation of sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate<ref>PMID:15960612</ref>. | ||
| - | See also [[Lysine-cysteine NOS bonds]]. | + | See also [[Calvin cycle]] and [[Lysine-cysteine NOS bonds]]. |
== Disease == | == Disease == | ||
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[[Transaldolase 3D structures]] | [[Transaldolase 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of transaldolase == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Transaldolase | ||
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| - | **[[1f05]] – TAL – human<br /> | ||
| - | **[[2cwn]], [[2e1d]] – TAL (mutant) – mouse<br /> | ||
| - | **[[3clm]], [[6zwf]], [[6zwh]], [[6zwj]], [[6zx4]], [[7b0l]], [[7odo]], [[7odp]], [[7odq]] –NgTAL – ''Neisseria gonorrhoeae''<br /> | ||
| - | **[[7bbw]], [[7bbx]], [[7oey]] - NgTAL (mutant) <br /> | ||
| - | **[[3cwn]], [[1onr]], [[1ucw]] - EcTAL B – ''Escherichia coli''<br /> | ||
| - | **[[3kof]], [[1i2n]], [[1i2o]], [[1i2p]], [[1i2q]], [[1i2r]], [[4rz5]], [[4rz6]] - EcTAL B (mutant)<br /> | ||
| - | **[[3hjz]] – TAL B – ''Prochlorococcus marinus''<br /> | ||
| - | **[[3igx]], [[4e0c]] – FtTAL B – ''Francisella tularensis''<br /> | ||
| - | **[[3m16]] – TAL – ''Oleispira Antarctica''<br /> | ||
| - | **[[3r8r]] – TAL – ''Bacillus subtilis''<br /> | ||
| - | **[[3r5e]] – TAL – ''Corynebacterium glutamicum''<br /> | ||
| - | **[[1vpx]] – TAL – ''Thermotoga maritima''<br /> | ||
| - | **[[1wx0]] – TAL – ''Thermus thermophilus''<br /> | ||
| - | **[[6yre]] - TaTAL – ''Thermoplasma acidophilum''<br /> | ||
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| - | *Transaldolase binary complexes | ||
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| - | **[[3tk7]] - FtTAL B + fructose 6-phosphate<br /> | ||
| - | **[[3te9]] - FtTAL B (mutant) + fructose 6-phosphate<br /> | ||
| - | **[[3tkf]] - FtTAL B (mutant) + seduheptulose 7-phosphate<br /`> | ||
| - | **[[3tno]] - FtTAL B + seduheptulose 7-phosphate<br /> | ||
| - | **[[3upb]] - FtTAL B + arabinose 5-phosphate<br /> | ||
| - | **[[4s2b]] - EcTAL B + tagatose 6-phosphate<br /> | ||
| - | **[[4s2c]], [[4s1f]] - EcTAL B + fructose 6-phosphate<br /> | ||
| - | **[[4rxf]], [[4rxg]], [[4rz4]] - EcTAL B (mutant) + fructose 6-phosphate<br /> | ||
| - | **[[4xz9]] - TaTAL + glycerol 3-phosphate <br /> | ||
| - | **[[6yr3]] - TaTAL + fructose 6-phosphate <br /> | ||
| - | **[[6yrh]], [[6yrm]], [[6yrt]] - TaTAL (mutant) + fructose 6-phosphate<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Caillau M, Paul Quick W. New insights into plant transaldolase. Plant J. 2005 Jul;43(1):1-16. PMID:15960612 doi:http://dx.doi.org/TPJ2427
- ↑ Qian Y, Banerjee S, Grossman CE, Amidon W, Nagy G, Barcza M, Niland B, Karp DR, Middleton FA, Banki K, Perl A. Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing. Biochem J. 2008 Oct 1;415(1):123-34. doi: 10.1042/BJ20080722. PMID:18498245 doi:http://dx.doi.org/10.1042/BJ20080722
- ↑ Light SH, Minasov G, Duban ME, Anderson WF. Adherence to Burgi-Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: insights from transaldolase complexes. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):544-52. doi:, 10.1107/S1399004713030666. Epub 2014 Jan 31. PMID:24531488 doi:http://dx.doi.org/10.1107/S1399004713030666
