This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7xk2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 7xk2 is ON HOLD Authors: Description: Category: Unreleased Structures)
Current revision (09:00, 6 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7xk2 is ON HOLD
+
==Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex==
-
 
+
<StructureSection load='7xk2' size='340' side='right'caption='[[7xk2]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[7xk2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XK2 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FI7:2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic+acid'>FI7</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xk2 OCA], [https://pdbe.org/7xk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xk2 RCSB], [https://www.ebi.ac.uk/pdbsum/7xk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xk2 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: DiBerto JF]]
 +
[[Category: Gao RG]]
 +
[[Category: Han GW]]
 +
[[Category: Kang HJ]]
 +
[[Category: Kenakin T]]
 +
[[Category: Li XM]]
 +
[[Category: Liu ZJ]]
 +
[[Category: Peng W]]
 +
[[Category: Pileski R]]
 +
[[Category: Qu L]]
 +
[[Category: Rao ZH]]
 +
[[Category: Roth BL]]
 +
[[Category: Stevens RC]]
 +
[[Category: Tong JH]]
 +
[[Category: Wang JJ]]
 +
[[Category: Wang Q]]
 +
[[Category: Wu LJ]]
 +
[[Category: Wu YR]]
 +
[[Category: Yang Y]]
 +
[[Category: Zhang XC]]
 +
[[Category: Zhao SW]]

Current revision

Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex

PDB ID 7xk2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7xk2"
Personal tools