Transcription initiation factors 3D structures

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Current revision (10:57, 31 December 2023) (edit) (undo)
 
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**[[5m4s]] – hTFIIA – human<br />
**[[5m4s]] – hTFIIA – human<br />
-
**[[6mzm]] – hTFIIA+TFIID + TBP + DNA – Cryo EM<br />
 
**[[1nvp]] – hTFIIA + TBP + DNA <br />
**[[1nvp]] – hTFIIA + TBP + DNA <br />
-
**[[5fur]] – hTFIIA + hTFIIF + TBP + DNA - CryoEM<br />
+
**[[6mzm]] – hTFIIA+TFIID + TBP + DNA – Cryo EM<br />
-
**[[1ytf]], [[1nh2]], [[1rm1]] – yTFIIA + TBP + DNA – yeast<br />
+
**[[1nh2]], [[1rm1]], [[1ytf]] – yTFIIA + TBP + DNA – yeast<br />
**[[7oh9]], [[7oha]] – yTFIIA in nucleosome complex - CryoEM<br />
**[[7oh9]], [[7oha]] – yTFIIA in nucleosome complex - CryoEM<br />
 +
**[[5fur]] – yTFIIA + yTFIIF + TBP + DNA - CryoEM<br />
*TFIIB
*TFIIB
-
**[[1tfb]] – hTFIIB - NMR<BR />
+
**[[1tfb]] – hTFIIB – NMR<br />
**[[1dl6]] - hTFIIB N terminal – NMR<br />
**[[1dl6]] - hTFIIB N terminal – NMR<br />
**[[5wh1]] - hTFIIB C terminal <br />
**[[5wh1]] - hTFIIB C terminal <br />
**[[1rly]] - hTFIIB Zn ribbon domain + Zn – NMR<br />
**[[1rly]] - hTFIIB Zn ribbon domain + Zn – NMR<br />
**[[1ro4]] - hTFIIB Zn ribbon domain – NMR<br />
**[[1ro4]] - hTFIIB Zn ribbon domain – NMR<br />
 +
**[[1c9b]], [[1vol]]  – hTFIIB + TBP + DNA<br />
**[[1ais]], [[1d3u]] - TFIIB C terminal + TBP + DNA – ''Pyrococcus woesei''<br />
**[[1ais]], [[1d3u]] - TFIIB C terminal + TBP + DNA – ''Pyrococcus woesei''<br />
-
**[[1pft]] – PfTFIIB N terminal – ''Pyrococcus furiosus'' – NMR<BR />
+
**[[1pft]] – PfTFIIB N terminal – ''Pyrococcus furiosus'' – NMR<br />
-
**[[5o9j]], [[5o9i]] - TFIIB – ''Methanocaldococcus jannaschii'' <br />
+
**[[5o9i]], [[5o9j]] - TFIIB – ''Methanocaldococcus jannaschii'' <br />
*TFIIA+TFIIB
*TFIIA+TFIIB
**[[6o9l]] – hTFIIA+TFIIB in RNA polymerase II – Cryo EM<br />
**[[6o9l]] – hTFIIA+TFIIB in RNA polymerase II – Cryo EM<br />
 +
**[[7zwc]] – hTFIIA+TFIIB + SNAPc:TBP – Cryo EM<br />
*TFIIIB
*TFIIIB
**[[5n9g]] – hTFIIIB + TBP + DNA<br />
**[[5n9g]] – hTFIIIB + TBP + DNA<br />
-
**[[6f44]], [[6f42]], [[6f41]], [[6f40]], [[6eu0]], [[6cnf]], [[6cnd]], [[6cnc]], [[6cnb]] – yTFIIIB + RNA polymerase III – Cryo EM<br />
+
**[[6f40]], [[6f41]], [[6f42]], [[6f44]], [[6cnb]], [[6cnc]], [[6cnd]], [[6cnf]], [[6eu0]] – yTFIIIB + RNA polymerase III – Cryo EM<br />
**[[7q5b]] – yTFIIIB in TY3 retrotransposon complex – Cryo EM<br />
**[[7q5b]] – yTFIIIB in TY3 retrotransposon complex – Cryo EM<br />
- 
-
*TFIIIC see [[Transcription factor tau]]
 
*TFIID
*TFIID
-
**[[1bh8]] – hTFIID<BR />
+
**[[1bh8]] – hTFIID<br />
**[[1eqf]], [[7k3o]] – hTFIID subunit 1<br />
**[[1eqf]], [[7k3o]] – hTFIID subunit 1<br />
**[[6fic]], [[7jjg]], [[7jjh]], [[7jsp]], [[7jtc]], [[7k03]], [[7k0d]], [[7k0u]], [[7k1p]], [[7k27]], [[7k42]], [[7k6f]], [[7l6x]], [[7lb0]], [[7lb1]], [[7lb2]], [[7lb3]], [[7n42]], [[7p4s]], [[7t2i]], [[7t36]] – hTFIID subunit 1 + inhibitor<br />
**[[6fic]], [[7jjg]], [[7jjh]], [[7jsp]], [[7jtc]], [[7k03]], [[7k0d]], [[7k0u]], [[7k1p]], [[7k27]], [[7k42]], [[7k6f]], [[7l6x]], [[7lb0]], [[7lb1]], [[7lb2]], [[7lb3]], [[7n42]], [[7p4s]], [[7t2i]], [[7t36]] – hTFIID subunit 1 + inhibitor<br />
**[[3uv5]] – hTFIID subunit 1 bromodomain 1-2<br />
**[[3uv5]] – hTFIID subunit 1 bromodomain 1-2<br />
**[[3uv4]] – hTFIID subunit 1 bromodomain 2 1501-1635<br />
**[[3uv4]] – hTFIID subunit 1 bromodomain 2 1501-1635<br />
-
**[[6bqd]], [[5mg2]], [[6p38]], [[6p3a]], [[6p39]] – hTFIID subunit 1 bromodomain 2 + inhibitor <br />
+
**[[5mg2]], [[6bqd]], [[6p38]], [[6p39]], [[6p3a]] – hTFIID subunit 1 bromodomain 2 + inhibitor <br />
**[[3aad]] – hTFIID subunit 1 bromodomain 1-2 + histone chaperone ASF1A<br />
**[[3aad]] – hTFIID subunit 1 bromodomain 1-2 + histone chaperone ASF1A<br />
-
**[[5mg2]] – hTFIID subunit 1 bromodomain 2 + inhibitor<br />
 
**[[4yym]], [[4yyn]] – hTFIID subunit 1 bromodomain 2 + histone peptide<br />
**[[4yym]], [[4yyn]] – hTFIID subunit 1 bromodomain 2 + histone peptide<br />
**[[5i1q]], [[5i29]] – hTFIID subunit 1 bromodomain 2 + pyrrolopyridone<br />
**[[5i1q]], [[5i29]] – hTFIID subunit 1 bromodomain 2 + pyrrolopyridone<br />
-
**[[5c13]], [[5wxg]], [[5wxh]], [[5mxy]] – hTFIID subunit 3 PHD finger + histone peptide<br />
+
**[[5c13]], [[5wxg]], [[5wxh]], [[5xmy]] – hTFIID subunit 3 PHD finger 853-915 + histone peptide<br />
-
**[[5wxh]] – hTFIID subunit 3 PHD finger + histone peptide<br />
+
**[[5eg2]] - hTFIID subunit 10 + SETD7 + SAH<br />
**[[4wv4]] - hTFIID subunits 8+10 <br />
**[[4wv4]] - hTFIID subunits 8+10 <br />
**[[4grw]] - hTFIID subunits 1+7 <br />
**[[4grw]] - hTFIID subunits 1+7 <br />
**[[6f3t]] - hTFIID subunits 5+6+9 <br />
**[[6f3t]] - hTFIID subunits 5+6+9 <br />
-
**[[6mzl]], [[7eg9]], [[7egb]], [[7egc]], [[7ege]], [[7ena]], [[7enc]] - hTFIID subunits 1-13 + TBP – Cryo EM<br />
+
**[[6mzl]], [[7eg9]], [[7egb]], [[7egc]], [[7ege]], [[7ena]], [[7enc]] - hTFIID subunits 1-13 + TBP – Cryo EM<br />
**[[6mzd]], [[7egf]] - hTFIID subunits 1,3-6,9-13 + TBP – Cryo EM<br />
**[[6mzd]], [[7egf]] - hTFIID subunits 1,3-6,9-13 + TBP – Cryo EM<br />
**[[6mzc]], [[7egg]] - hTFIID subunits 2,4-6,8-12 – Cryo EM<br />
**[[6mzc]], [[7egg]] - hTFIID subunits 2,4-6,8-12 – Cryo EM<br />
**[[7egh]] - hTFIID subunits 1,2,6-8 + DNA – Cryo EM<br />
**[[7egh]] - hTFIID subunits 1,2,6-8 + DNA – Cryo EM<br />
-
**[[7ktr]], [[7kts]] - hTFIID in SAGA coactivator complex – Cryo EM<br />At
+
**[[7ktr]], [[7kts]], [[8h7g]] - hTFIID in SAGA coactivator complex – Cryo EM<br />
-
**[[1bh9]] – hTFIID + PCMBS<BR />
+
**[[1bh9]] – hTFIID + PCMBS<br />
-
**[[6df7]], [[6df4]] – TFIID subunit 1 bromodomain 2 + inhibitor - rabbit<br />
+
**[[6df4]], [[6df7]] – TFIID subunit 1 bromodomain 2 + inhibitor - rabbit<br />
-
**[[1tba]] – TFIID – ''Drosophila melanogaster'' - NMR<BR />
+
**[[1tba]] – TFIID – ''Drosophila melanogaster'' - NMR<br />
-
**[[1qn3]], [[1qn4]], [[1qn5]], [[1qn6]], [[1qn7]], [[1qn8]], [[1qn9]], [[1qna]], [[1qnb]], [[1qnc]], [[1qne]] – TFIID + DNA – ''Arabidopsis thaliana''<br />
+
**[[1qn3]], [[1qn4]], [[1qn5]], [[1qn6]], [[1qn7]], [[1qn8]], [[1qn9]], [[1qna]], [[1qnb]], [[1qnc]], [[1qne]] – AtTFIID + DNA
 +
''Arabidopsis thaliana''<br />
**[[7ac1]] - AtTFIID subunit 4 RST domain - NMR<br />
**[[7ac1]] - AtTFIID subunit 4 RST domain - NMR<br />
**[[4oy2]] - yTFIID subunits 1+7 <br />
**[[4oy2]] - yTFIID subunits 1+7 <br />
-
**[[6mip]] - yTFIID subunits 14 <br />
+
**[[6mip]] - yTFIID subunit 14 <br />
**[[6lqz]] - yTFIID subunit 14 + STH1EBMC - NMR<br />
**[[6lqz]] - yTFIID subunit 14 + STH1EBMC - NMR<br />
-
**[[5iok]], [[5d7e]], [[6miq]], [[6mio]], [[6min]], [[7f4a]] – yTFIID subunit 14 YEATS domain 1-137 + histone peptide<br />
+
**[[5d7e]], [[5iok]], [[6min]], [[6mio]], [[6miq]], [[7f4a]] – yTFIID subunit 14 YEATS domain 1-137 + histone peptide<br />
 +
**[[7uhe]] – yTFIID subunit 14 ET domain 168-243 + C-terminal domain 1392-1403<br />
**[[6t9j]] - yTFIID subunit 12 + Spt20 + transcription-associated protein – Cryo EM <br />
**[[6t9j]] - yTFIID subunit 12 + Spt20 + transcription-associated protein – Cryo EM <br />
-
**[[6t9k]], [[6t9i]] - yTFIID in SAGA complex – Cryo EM <br />
+
**[[6t9i]], [[6t9k]] - yTFIID in SAGA complex – Cryo EM <br />
-
**[[6tbm]], [[6tb4]], [[6hqa]] - TFIID in SAGA complex – ''Komagataella phaffii'' – Cryo EM <br />
+
**[[6hqa]], [[6tb4]], [[6tbm]] - TFIID in SAGA complex –'' Komagataella phaffii'' – Cryo EM <br />
*TFIID+TFIIA
*TFIID+TFIIA
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*TFIIE
*TFIIE
-
**[[5gpy]] - hTFIIE subunits α 1-217+β 141-217<br />
+
**[[7nvw]], [[7nvx]] – hTFIIE + TFIIH + Mat1 + DNA – Cryo EM<br />
 +
**[[5gpy]] - hTFIIE subunit 1 1-217 + subunit 2 141-217<br />
**[[1vd4]] - hTFIIE Zn finger domain 113-174 – NMR<br />
**[[1vd4]] - hTFIIE Zn finger domain 113-174 – NMR<br />
**[[2rnq]] – hTFIIE C terminal 378-439 - NMR<br />
**[[2rnq]] – hTFIIE C terminal 378-439 - NMR<br />
**[[2rnr]] – hTFIIE C terminal + TFIIH PH domain- NMR<br />
**[[2rnr]] – hTFIIE C terminal + TFIIH PH domain- NMR<br />
-
**[[6xjf]], [[6pln]] – PfTFIIE-a <br />
+
**[[6pin]], [[6xjf]] – PfTFIIE-a <br />
*TFIIF
*TFIIF
Line 93: Line 95:
**[[7mei]], [[7mk9]] – yTFIIH in trailing EC complex – Cryo EM<br />
**[[7mei]], [[7mk9]] – yTFIIH in trailing EC complex – Cryo EM<br />
-
*TFIIH
+
* TFIIH
**[[5ivw]], [[6o9m]], [[7o4k]], [[7o4l]] – hTFIIH in preinitiation complex – Cryo EM<br />
**[[5ivw]], [[6o9m]], [[7o4k]], [[7o4l]] – hTFIIH in preinitiation complex – Cryo EM<br />
Line 101: Line 103:
**[[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hTFIIA + hTFIIB + hTFIIE + hTFIIF + hTFIIH + DNA – Cryo EM<br />
**[[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hTFIIA + hTFIIB + hTFIIE + hTFIIF + hTFIIH + DNA – Cryo EM<br />
**[[7edx]], [[7eg7]], [[7eg8]], [[7eg9]], [[7ega]], [[7nvv]], [[7nvy]], [[7nvz]], [[7nw0]] – hTFII in RNA polymerase – Cryo EM<br />
**[[7edx]], [[7eg7]], [[7eg8]], [[7eg9]], [[7ega]], [[7nvv]], [[7nvy]], [[7nvz]], [[7nw0]] – hTFII in RNA polymerase – Cryo EM<br />
 +
**[[8wb0]] – hTFIIF + in RNA polymerase II transcription pre-initiation complex - CryoEM<br />
 +
**[[8iue]], [[8iuh]] – hTFIID + in RNA polymerase III pre-initiation complex - CryoEM<br />
 +
**[[7nvr]], [[7nvs]], [[7nvt]], [[7nvu]] – hTFIIA + TFIIB + TFIIE + TFIIF + in mediator with RNA polymerase II transcription pre-initiation complex - CryoEM<br />
**[[5fyw]] – yTFIIA + yTFIIE + yTFIIF + DNA <br />
**[[5fyw]] – yTFIIA + yTFIIE + yTFIIF + DNA <br />
-
**[[5fz5]], [[6gym]], [[6gyl]] – yTFIIA + yTFIIE + yTFIIF + DNA – Cryo EM<br />
+
**[[5fz5]], [[6gyl]], [[6gym]] – yTFIIA + yTFIIE + yTFIIF + DNA – Cryo EM<br />
**[[6gyk]] – yTFIIA + yTFIIB + yTFIIF + DNA – Cryo EM<br />
**[[6gyk]] – yTFIIA + yTFIIB + yTFIIF + DNA – Cryo EM<br />
**[[5sva]] – yTFIIA + yTFIIB + yTFIIE + yTFIIF + DNA – Cryo EM<br />
**[[5sva]] – yTFIIA + yTFIIB + yTFIIE + yTFIIF + DNA – Cryo EM<br />
-
**[[4v1o]], [[4v1n]] – yTFIIB + yTFIIF – Cryo EM<br />
+
**[[4v1n]], [[4v1o]] – yTFIIB + yTFIIF – Cryo EM<br />
-
**[[3k1f]], [[3k7a]], [[4bbr]], [[4bbs]] – yTFIIB <br />
+
**[[7ml0]], [[7ml2]], [[7ml4]] - yTFIIB + TFIIE + TFIIF + in RNA polymerase II pre-initiation complex - CryoEM<br />
 +
**[[3k1f]], [[3k7a]], [[4bbr]], [[4bbs]] – yTFIIB in RNA polymerase complex<br />
 +
**[[7o72]] – yTFIIB in RNA polymerase II transcription pre-initiation complex - CryoEM<br />
 +
**[[7o73]] – yTFIIA + TFIIE + TFIIF + in RNA polymerase II transcription pre-initiation complex - CryoEM<br />
 +
**[[7o4i]], [[7o4j]], [[7o75]] – yTFIIA + TFIIB + TFIIE + TFIIF + in RNA polymerase II transcription pre-initiation complex - CryoEM<br />
 +
**[[7zs9]], [[7zsa]], [[7zsb]], [[8bz1]] – yTFIIA + TFIIB + TFIID + TFIIE + TFIIF + nucleosome in RNA polymerase II transcription pre-initiation complex - CryoEM<br />
**[[5fmf]], [[5oqj]], [[5oqm]] – yTFIIA + yTFIIB + yTFIIE + yTFIIF + yTFIIH + DNA – Cryo EM<br />
**[[5fmf]], [[5oqj]], [[5oqm]] – yTFIIA + yTFIIB + yTFIIE + yTFIIF + yTFIIH + DNA – Cryo EM<br />
**[[6kf4]], [[6kf9]] – TFIIF – ''Thermococcus kodakarensis'' - Cryo EM<br />
**[[6kf4]], [[6kf9]] – TFIIF – ''Thermococcus kodakarensis'' - Cryo EM<br />
Line 115: Line 125:
**[[3tj1]] – yTF RRN3 <br />
**[[3tj1]] – yTF RRN3 <br />
**[[5g5l]] – yTF RRN3 in RNA polymerase I<br />
**[[5g5l]] – yTF RRN3 in RNA polymerase I<br />
-
**[[6rrd]], [[6rqt]] – yTF RRN3 in RNA polymerase I – Cryo EM<br />
+
**[[6rqt]], [[6rrd]] – yTF RRN3 in RNA polymerase I – Cryo EM<br />
-
**[[5o7x]] – yTF RRN6+RRN7+RRN11 <br />
+
**[[6ruo]] – yTF RRN3+RRN6+RRN11 in RNA polymerase I – Cryo EM<br />
**[[6ruo]] – yTF RRN3+RRN6+RRN11 in RNA polymerase I – Cryo EM<br />
-
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]], [[5oa1]] – yTF RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br />
+
**[[5o7x]] – yTF RRN6+RRN7+RRN11 <br />
-
**[[6rwe]], [[6rui]], [[6rql]], [[6rqh]], [[5n61]], [[5n60]], [[5n5z]], [[5n5y]] – yTF RRN3+RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br />
+
**[[5oa1]], [[5w5y]], [[5w64]], [[5w65]], [[5w66]] – yTF RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br />
-
**[[7z0o]] – yTF RRN5+RRN9+RRN10 in RNA polymerase I – Cryo EM<br />
+
**[[5n5y]], [[5n5z]], [[5n60]], [[5n61]], [[6rqh]], [[6rql]], [[6rui]], [[6rwe]] – yTF RRN3+RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br />
 +
**[[7z0o]] – yTF RRN5+RRN9+RRN10 in RNA polymerase I – Cryo EM<br />
 +
 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of transcription initiation factors

Updated on 31-December-2023 - For a general description of the protein see Transcription initiation factor

Arabidopsis thaliana

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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