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7l92
From Proteopedia
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==C1B domain of Protein kinase C in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate== | ==C1B domain of Protein kinase C in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate== | ||
| - | <StructureSection load='7l92' size='340' side='right'caption='[[7l92]]' scene=''> | + | <StructureSection load='7l92' size='340' side='right'caption='[[7l92]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L92 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7l92]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L92 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l92 OCA], [https://pdbe.org/7l92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l92 RCSB], [https://www.ebi.ac.uk/pdbsum/7l92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l92 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=DPV:DODECYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>DPV</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l92 OCA], [https://pdbe.org/7l92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l92 RCSB], [https://www.ebi.ac.uk/pdbsum/7l92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l92 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A140UHX0_RAT A0A140UHX0_RAT] Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.[PIRNR:PIRNR000551] | ||
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| + | ==See Also== | ||
| + | *[[Protein kinase C 3D structures|Protein kinase C 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
[[Category: Katti SS]] | [[Category: Katti SS]] | ||
[[Category: Krieger IV]] | [[Category: Krieger IV]] | ||
Current revision
C1B domain of Protein kinase C in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
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