This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7lcb
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine== | ==C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine== | ||
| - | <StructureSection load='7lcb' size='340' side='right'caption='[[7lcb]]' scene=''> | + | <StructureSection load='7lcb' size='340' side='right'caption='[[7lcb]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LCB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7lcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LCB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lcb OCA], [https://pdbe.org/7lcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lcb RCSB], [https://www.ebi.ac.uk/pdbsum/7lcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lcb ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XP5:(4S,7R)-7-(HEPTANOYLOXY)-4-HYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEXADECAN-1-AMINIUM+4-OXIDE'>XP5</scene>, <scene name='pdbligand=XYV:prostratin'>XYV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lcb OCA], [https://pdbe.org/7lcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lcb RCSB], [https://www.ebi.ac.uk/pdbsum/7lcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lcb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A140UHX0_RAT A0A140UHX0_RAT] Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.[PIRNR:PIRNR000551] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Protein kinase C 3D structures|Protein kinase C 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
[[Category: Katti SS]] | [[Category: Katti SS]] | ||
[[Category: Krieger IV]] | [[Category: Krieger IV]] | ||
Current revision
C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine
| |||||||||||
