7r51
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Structure of P. gingivalis DPP11 in complex with the dipeptide Arg-Asp== |
| - | <StructureSection load='7r51' size='340' side='right'caption='[[7r51]]' scene=''> | + | <StructureSection load='7r51' size='340' side='right'caption='[[7r51]], [[Resolution|resolution]] 1.81Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7r51]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R51 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r51 OCA], [https://pdbe.org/7r51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r51 RCSB], [https://www.ebi.ac.uk/pdbsum/7r51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r51 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.808Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r51 OCA], [https://pdbe.org/7r51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r51 RCSB], [https://www.ebi.ac.uk/pdbsum/7r51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r51 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPP11_PORG3 DPP11_PORG3] Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA. Is involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.<ref>PMID:21896480</ref> <ref>PMID:23246913</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Porphyromonas gingivalis]] |
| + | [[Category: Bezerra GA]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Coker JA]] | ||
| + | [[Category: Foster WR]] | ||
| + | [[Category: Nemoto TK]] | ||
| + | [[Category: Ohara-Nemoto Y]] | ||
| + | [[Category: Tham CT]] | ||
| + | [[Category: Yue WW]] | ||
Current revision
Structure of P. gingivalis DPP11 in complex with the dipeptide Arg-Asp
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