6zx0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:48, 23 October 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='6zx0' size='340' side='right'caption='[[6zx0]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='6zx0' size='340' side='right'caption='[[6zx0]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6zx0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZX0 FirstGlance]. <br>
+
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZX0 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zx0 OCA], [https://pdbe.org/6zx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zx0 RCSB], [https://www.ebi.ac.uk/pdbsum/6zx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zx0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zx0 OCA], [https://pdbe.org/6zx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zx0 RCSB], [https://www.ebi.ac.uk/pdbsum/6zx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zx0 ProSAT]</span></td></tr>
</table>
</table>
-
== Disease ==
+
 
-
[[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN]] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[https://omim.org/entry/258900 258900]]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>
+
==See Also==
-
== References ==
+
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Krull, M]]
+
[[Category: Krull M]]
-
[[Category: Rindfleisch, S]]
+
[[Category: Rindfleisch S]]
-
[[Category: Tittmann, K]]
+
[[Category: Tittmann K]]
-
[[Category: Lyase]]
+
-
[[Category: Omp]]
+
-
[[Category: Ompd]]
+
-
[[Category: Orotidine 5'-monophosphate decarboxylase]]
+
-
[[Category: Ump]]
+

Current revision

OMPD-domain of human UMPS in complex with the substrate OMP at 1.25 Angstroms resolution

PDB ID 6zx0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools