7ulx

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'''Unreleased structure'''
 
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The entry 7ulx is ON HOLD until Paper Publication
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==Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine==
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<StructureSection load='7ulx' size='340' side='right'caption='[[7ulx]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
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Authors: Zheng, Y., Butrin, A., Tuley, A., Liu, D., Fast, W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ulx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ULX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ULX FirstGlance]. <br>
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Description: Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.707&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NQ6:(2~{S})-2-azanyl-4-oxidanylidene-4-(pyridin-2-ylamino)butanoic+acid'>NQ6</scene></td></tr>
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[[Category: Liu, D]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ulx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ulx OCA], [https://pdbe.org/7ulx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ulx RCSB], [https://www.ebi.ac.uk/pdbsum/7ulx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ulx ProSAT]</span></td></tr>
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[[Category: Butrin, A]]
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</table>
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[[Category: Zheng, Y]]
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== Function ==
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[[Category: Fast, W]]
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[https://www.uniprot.org/uniprot/DDAH1_HUMAN DDAH1_HUMAN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
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[[Category: Tuley, A]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Butrin A]]
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[[Category: Fast W]]
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[[Category: Liu D]]
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[[Category: Tuley A]]
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[[Category: Zheng Y]]

Current revision

Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine

PDB ID 7ulx

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OCA

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