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7xs6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7xs6 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==structure of a membrane-integrated glycosyltransferase with inhibitor== | |
| - | + | <StructureSection load='7xs6' size='340' side='right'caption='[[7xs6]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XS6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0V9:(19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl+(9Z)-hexadec-9-enoate'>0V9</scene>, <scene name='pdbligand=BGI:(2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic+acid+(non-preferred+name)'>BGI</scene>, <scene name='pdbligand=C14:TETRADECANE'>C14</scene>, <scene name='pdbligand=D12:DODECANE'>D12</scene>, <scene name='pdbligand=HP6:HEPTANE'>HP6</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xs6 OCA], [https://pdbe.org/7xs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xs6 RCSB], [https://www.ebi.ac.uk/pdbsum/7xs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xs6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CHS1_YEAST CHS1_YEAST] Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (PubMed:2941152). Required for mitotic division septum formation during adverse conditions (PubMed:2523889).<ref>PMID:2523889</ref> <ref>PMID:2941152</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Ding XY]] | ||
| + | [[Category: Liu XT]] | ||
| + | [[Category: Wu YN]] | ||
| + | [[Category: Yang YZ]] | ||
| + | [[Category: Yu HJ]] | ||
| + | [[Category: Zhang M]] | ||
| + | [[Category: Zhang MJ]] | ||
Current revision
structure of a membrane-integrated glycosyltransferase with inhibitor
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Categories: Large Structures | Saccharomyces cerevisiae | Ding XY | Liu XT | Wu YN | Yang YZ | Yu HJ | Zhang M | Zhang MJ
