This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7zt4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7zt4 is ON HOLD Authors: Karuppiah, V., Robinson, R.A. Description: Structure of E8 TCR in complex with human MR1 bound to 6FP [[Category: Unreleas...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of E8 TCR in complex with human MR1 bound to 6FP== | |
| - | + | <StructureSection load='7zt4' size='340' side='right'caption='[[7zt4]], [[Resolution|resolution]] 2.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zt4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZT4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JSO:2-azanyl-6-methyl-3~{H}-pteridin-4-one'>JSO</scene></td></tr> |
| - | [[Category: Karuppiah | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zt4 OCA], [https://pdbe.org/7zt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zt4 RCSB], [https://www.ebi.ac.uk/pdbsum/7zt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zt4 ProSAT]</span></td></tr> |
| - | [[Category: Robinson | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Karuppiah V]] | ||
| + | [[Category: Robinson RA]] | ||
Current revision
Structure of E8 TCR in complex with human MR1 bound to 6FP
| |||||||||||
