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7oj4

From Proteopedia

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<StructureSection load='7oj4' size='340' side='right'caption='[[7oj4]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='7oj4' size='340' side='right'caption='[[7oj4]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7oj4]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7ay4 7ay4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OJ4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7oj4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tick-borne_encephalitis_virus Tick-borne encephalitis virus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7ay4 7ay4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OJ4 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7blv|7blv]], [[7bm0|7bm0]], [[7nxu|7nxu]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.828&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oj4 OCA], [https://pdbe.org/7oj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7oj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oj4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oj4 OCA], [https://pdbe.org/7oj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7oj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oj4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/A0A2S1PWV0_9FLAV A0A2S1PWV0_9FLAV]] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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[https://www.uniprot.org/uniprot/A0A2S1PWV0_9FLAV A0A2S1PWV0_9FLAV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
==See Also==
==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
*[[Nonstructural protein 3D structures|Nonstructural protein 3D structures]]
*[[Nonstructural protein 3D structures|Nonstructural protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: RNA helicase]]
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[[Category: Tick-borne encephalitis virus]]
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[[Category: Anindita, P D]]
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[[Category: Anindita PD]]
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[[Category: Brynda, J]]
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[[Category: Brynda J]]
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[[Category: Franta, Z]]
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[[Category: Franta Z]]
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[[Category: Grinkevich, P]]
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[[Category: Grinkevich P]]
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[[Category: Havlickova, P]]
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[[Category: Havlickova P]]
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[[Category: Kascakova, B]]
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[[Category: Kascakova B]]
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[[Category: Hydrolase]]
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[[Category: Non-structural protein]]
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[[Category: Rna helicase]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of apo NS3 helicase from tick-borne encephalitis virus

PDB ID 7oj4

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