This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7xt0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7xt0 is ON HOLD Authors: Wang, D.P., Jiang, F.Y., Zeng, X.Y., Zhao, R., Chen, C., Zhu, Y., Cao, J.M. Description: Crystal structure of RNA helicase...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors== | |
| - | + | <StructureSection load='7xt0' size='340' side='right'caption='[[7xt0]], [[Resolution|resolution]] 2.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xt0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saint_Louis_encephalitis_virus Saint Louis encephalitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XT0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XT0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xt0 OCA], [https://pdbe.org/7xt0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xt0 RCSB], [https://www.ebi.ac.uk/pdbsum/7xt0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xt0 ProSAT]</span></td></tr> |
| - | [[Category: Cao | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/A0A6M5UNY4_9FLAV A0A6M5UNY4_9FLAV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Saint Louis encephalitis virus]] | ||
| + | [[Category: Cao JM]] | ||
| + | [[Category: Chen C]] | ||
| + | [[Category: Jiang FY]] | ||
| + | [[Category: Wang DP]] | ||
| + | [[Category: Zeng XY]] | ||
| + | [[Category: Zhao R]] | ||
| + | [[Category: Zhu Y]] | ||
Current revision
Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors
| |||||||||||
Categories: Large Structures | Saint Louis encephalitis virus | Cao JM | Chen C | Jiang FY | Wang DP | Zeng XY | Zhao R | Zhu Y
