This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7em6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:56, 29 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7em6' size='340' side='right'caption='[[7em6]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<StructureSection load='7em6' size='340' side='right'caption='[[7em6]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7em6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM6 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7em6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM6 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZU:[[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>CZU</scene>, <scene name='pdbligand=IDP:INOSINE-5-DIPHOSPHATE'>IDP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZU:[[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>CZU</scene>, <scene name='pdbligand=IDP:INOSINE-5-DIPHOSPHATE'>IDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em6 OCA], [https://pdbe.org/7em6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em6 RCSB], [https://www.ebi.ac.uk/pdbsum/7em6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em6 OCA], [https://pdbe.org/7em6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em6 RCSB], [https://www.ebi.ac.uk/pdbsum/7em6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
+
[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Senda, M]]
+
[[Category: Senda M]]
-
[[Category: Senda, T]]
+
[[Category: Senda T]]
-
[[Category: Lipid kinase]]
+
-
[[Category: Phosphoinositide signaling]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of the PI5P4Kbeta N203D-ITP complex

PDB ID 7em6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7em6"
Personal tools