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3pso
From Proteopedia
(Difference between revisions)
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<StructureSection load='3pso' size='340' side='right'caption='[[3pso]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='3pso' size='340' side='right'caption='[[3pso]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3pso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh6 3lh6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [https://pdbe.org/3pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [https://www.ebi.ac.uk/pdbsum/3pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pso ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [https://pdbe.org/3pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [https://www.ebi.ac.uk/pdbsum/3pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pso ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | |
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Chhabra | + | [[Category: Chhabra S]] |
| - | [[Category: Collins | + | [[Category: Collins B]] |
| - | [[Category: Ghai | + | [[Category: Ghai R]] |
| - | [[Category: Norwood | + | [[Category: Norwood S]] |
| - | [[Category: Shaw | + | [[Category: Shaw D]] |
| - | [[Category: Swarbrick | + | [[Category: Swarbrick J]] |
| - | [[Category: Valkov | + | [[Category: Valkov E]] |
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Current revision
Crystal structure of mouse VPS29 complexed with Zn2+
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Categories: Large Structures | Mus musculus | Chhabra S | Collins B | Ghai R | Norwood S | Shaw D | Swarbrick J | Valkov E
