3pv6
From Proteopedia
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<StructureSection load='3pv6' size='340' side='right'caption='[[3pv6]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3pv6' size='340' side='right'caption='[[3pv6]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pv6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3pv6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PV6 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pv6 OCA], [https://pdbe.org/3pv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pv6 RCSB], [https://www.ebi.ac.uk/pdbsum/3pv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pv6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pv6 OCA], [https://pdbe.org/3pv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pv6 RCSB], [https://www.ebi.ac.uk/pdbsum/3pv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pv6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref> | |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Li | + | [[Category: Li Y]] |
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Current revision
Crystal structure of NKp30 bound to its ligand B7-H6
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