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3pya

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Current revision (13:35, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3pya' size='340' side='right'caption='[[3pya]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='3pya' size='340' side='right'caption='[[3pya]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PYA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PYA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=AG8:S-[(2E,6E,10E)-14-(DIMETHYLAMINO)-3,7,11-TRIMETHYLTETRADECA-2,6,10-TRIEN-1-YL]+TRIHYDROGEN+THIODIPHOSPHATE'>AG8</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At4g02780, GA1, T5J8.9, TPSGA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=AG8:S-[(2E,6E,10E)-14-(DIMETHYLAMINO)-3,7,11-TRIMETHYLTETRADECA-2,6,10-TRIEN-1-YL]+TRIHYDROGEN+THIODIPHOSPHATE'>AG8</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ent-copalyl_diphosphate_synthase Ent-copalyl diphosphate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.13 5.5.1.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pya OCA], [https://pdbe.org/3pya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pya RCSB], [https://www.ebi.ac.uk/pdbsum/3pya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pya ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pya OCA], [https://pdbe.org/3pya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pya RCSB], [https://www.ebi.ac.uk/pdbsum/3pya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pya ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/KSA_ARATH KSA_ARATH]] Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate.<ref>PMID:17457817</ref> <ref>PMID:20430888</ref>
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[https://www.uniprot.org/uniprot/KSA_ARATH KSA_ARATH] Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate.<ref>PMID:17457817</ref> <ref>PMID:20430888</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Ent-copalyl diphosphate synthase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Christianson, D W]]
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[[Category: Christianson DW]]
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[[Category: Koksal, M]]
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[[Category: Koksal M]]
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[[Category: Biosynthesis of ent-copalyl diphosphate]]
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[[Category: Class i and ii terpene cyclase fold]]
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[[Category: Class ii diterpene cyclase]]
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[[Category: Dxxdd motif]]
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[[Category: Gibberellin biosynthesis]]
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[[Category: Isomerase]]
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Current revision

Crystal structure of ent-copalyl diphosphate synthase from Arabidopsis thaliana in complex with (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate

PDB ID 3pya

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