7zy6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST== | |
| - | + | <StructureSection load='7zy6' size='340' side='right'caption='[[7zy6]], [[Resolution|resolution]] 3.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zy6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZY6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCI:5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine'>KCI</scene></td></tr> |
| - | [[Category: Graedler | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zy6 OCA], [https://pdbe.org/7zy6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zy6 RCSB], [https://www.ebi.ac.uk/pdbsum/7zy6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zy6 ProSAT]</span></td></tr> |
| - | [[Category: Lammens | + | </table> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Graedler U]] | ||
| + | [[Category: Lammens A]] | ||
Current revision
Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
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