8d1h
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==hBest2 Ca2+-unbound closed state== | |
| + | <StructureSection load='8d1h' size='340' side='right'caption='[[8d1h]], [[Resolution|resolution]] 1.94Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8d1h]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D1H FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.94Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DU0:2-[2-[(1~{S},2~{S},4~{S},5~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2-oxane]-16-yl]oxyethyl]propane-1,3-diol'>DU0</scene>, <scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d1h OCA], [https://pdbe.org/8d1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d1h RCSB], [https://www.ebi.ac.uk/pdbsum/8d1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d1h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BEST2_HUMAN BEST2_HUMAN] Forms calcium-sensitive chloride channels. Permeable to bicarbonate.<ref>PMID:11904445</ref> <ref>PMID:12907679</ref> <ref>PMID:18400985</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Bestrophin 3D structures|Bestrophin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hendrickson WA]] | ||
| + | [[Category: Kittredge A]] | ||
| + | [[Category: Owji AP]] | ||
| + | [[Category: Tingting Y]] | ||
Current revision
hBest2 Ca2+-unbound closed state
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