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8d44
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-electron microscopy structure of human kidney Fructose-bisphosphate aldolase B== | |
| - | + | <StructureSection load='8d44' size='340' side='right'caption='[[8d44]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8d44]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D44 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d44 OCA], [https://pdbe.org/8d44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d44 RCSB], [https://www.ebi.ac.uk/pdbsum/8d44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d44 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Lyu | + | [https://www.uniprot.org/uniprot/ALDOB_HUMAN ALDOB_HUMAN] Defects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:[https://omim.org/entry/229600 229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.<ref>PMID:10970798</ref> <ref>PMID:3383242</ref> <ref>PMID:1967768</ref> <ref>PMID:8299883</ref> <ref>PMID:8162030</ref> <ref>PMID:2336380</ref> <ref>PMID:10024431</ref> <ref>PMID:12205126</ref> <ref>PMID:15532022</ref> <ref>PMID:15880727</ref> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALDOB_HUMAN ALDOB_HUMAN] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lyu M]] | ||
| + | [[Category: Yu EW]] | ||
Current revision
Cryo-electron microscopy structure of human kidney Fructose-bisphosphate aldolase B
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