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7fee
From Proteopedia
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==Crystal Structure of protein l== | ==Crystal Structure of protein l== | ||
| - | <StructureSection load='7fee' size='340' side='right'caption='[[7fee]]' scene=''> | + | <StructureSection load='7fee' size='340' side='right'caption='[[7fee]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FEE FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7fee]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FEE FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fee OCA], [https://pdbe.org/7fee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fee RCSB], [https://www.ebi.ac.uk/pdbsum/7fee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fee ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7IC:6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole'>7IC</scene>, <scene name='pdbligand=9GF:2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol'>9GF</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fee OCA], [https://pdbe.org/7fee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fee RCSB], [https://www.ebi.ac.uk/pdbsum/7fee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fee ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] [https://www.uniprot.org/uniprot/CNR1_HUMAN CNR1_HUMAN] Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.<ref>PMID:15620723</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Pyrococcus abyssi GE5]] | ||
[[Category: Shao Z]] | [[Category: Shao Z]] | ||
[[Category: Wang X]] | [[Category: Wang X]] | ||
[[Category: Zhao C]] | [[Category: Zhao C]] | ||
Current revision
Crystal Structure of protein l
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