3rbg

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<StructureSection load='3rbg' size='340' side='right'caption='[[3rbg]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3rbg' size='340' side='right'caption='[[3rbg]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rbg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rbg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRTAM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbg OCA], [https://pdbe.org/3rbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbg RCSB], [https://www.ebi.ac.uk/pdbsum/3rbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbg OCA], [https://pdbe.org/3rbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbg RCSB], [https://www.ebi.ac.uk/pdbsum/3rbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CRTAM_HUMAN CRTAM_HUMAN]] Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.<ref>PMID:15811952</ref> [UniProtKB:Q149L7]
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[https://www.uniprot.org/uniprot/CRTAM_HUMAN CRTAM_HUMAN] Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.<ref>PMID:15811952</ref> [UniProtKB:Q149L7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Fiser, A]]
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[[Category: Fiser A]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network]]
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[[Category: Nathenson SG]]
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[[Category: Structural genomic]]
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[[Category: Ramagopal UA]]
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[[Category: Nathenson, S G]]
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[[Category: Rubinstein R]]
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[[Category: Ramagopal, U A]]
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[[Category: Toro R]]
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[[Category: Rubinstein, R]]
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[[Category: Toro, R]]
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[[Category: Atoms-to-animals: the immune function network]]
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[[Category: Crtam]]
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[[Category: Ifn]]
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[[Category: Igv]]
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[[Category: Immune system]]
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[[Category: Nysgrc]]
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[[Category: Psi-biology]]
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Current revision

Crystal structure analysis of Class-I MHC restricted T-cell associated molecule

PDB ID 3rbg

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