3rco

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Current revision (10:53, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3rco' size='340' side='right'caption='[[3rco]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3rco' size='340' side='right'caption='[[3rco]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rco]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RCO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rco]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RCO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TDRD7, PCTAIRE2BP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rco OCA], [https://pdbe.org/3rco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rco RCSB], [https://www.ebi.ac.uk/pdbsum/3rco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rco ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rco OCA], [https://pdbe.org/3rco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rco RCSB], [https://www.ebi.ac.uk/pdbsum/3rco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rco ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN]] The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN]] Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.<ref>PMID:21436445</ref>
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[https://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN] Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.<ref>PMID:21436445</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bian, C]]
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[[Category: Bian C]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Dong, A]]
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[[Category: Dong A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Guo, Y]]
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[[Category: Guo Y]]
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[[Category: Lam, R]]
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[[Category: Lam R]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Min, J]]
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[[Category: Min J]]
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[[Category: Structural genomic]]
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[[Category: Walker JR]]
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[[Category: Walker, J R]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Xu C]]
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[[Category: Xu, C]]
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[[Category: Dna binding protein]]
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[[Category: Hlh motif]]
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[[Category: Sgc]]
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Current revision

Crystal structure of a conserved motif in human TDRD7

PDB ID 3rco

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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