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7qw5

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Current revision (06:27, 25 January 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7qw5 is ON HOLD until 2024-01-24
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==Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex==
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<StructureSection load='7qw5' size='340' side='right'caption='[[7qw5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Mitsikas, D.A., Kouyianou, K., Kotsifaki, D., Providaki, M., Bouriotis, V., Glykos, N.M., Kokkinidis, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7qw5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QW5 FirstGlance]. <br>
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Description: Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qw5 OCA], [https://pdbe.org/7qw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qw5 RCSB], [https://www.ebi.ac.uk/pdbsum/7qw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qw5 ProSAT]</span></td></tr>
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[[Category: Bouriotis, V]]
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</table>
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[[Category: Glykos, N.M]]
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== Function ==
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[[Category: Mitsikas, D.A]]
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[https://www.uniprot.org/uniprot/MTC1_GEOSE MTC1_GEOSE] A gamma subtype methylase, recognizes the double-stranded sequence 5'-ATCGAT-3', methylation on A-5 on both strands, and protects the DNA from cleavage by the BanIII endonuclease.<ref>PMID:12654995</ref>
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[[Category: Providaki, M]]
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== References ==
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[[Category: Kouyianou, K]]
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<references/>
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[[Category: Kotsifaki, D]]
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__TOC__
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[[Category: Kokkinidis, M]]
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</StructureSection>
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Large Structures]]
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[[Category: Bouriotis V]]
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[[Category: Glykos NM]]
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[[Category: Kokkinidis M]]
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[[Category: Kotsifaki D]]
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[[Category: Kouyianou K]]
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[[Category: Mitsikas DA]]
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[[Category: Providaki M]]

Current revision

Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex

PDB ID 7qw5

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