7qxf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:07, 17 October 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7qxf is ON HOLD until Paper Publication
+
==Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand==
-
 
+
<StructureSection load='7qxf' size='340' side='right'caption='[[7qxf]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
-
Authors: Dobritzsch, D., Widersten, M., Engel, S.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[7qxf]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QXF FirstGlance]. <br>
-
Description: Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I2F:(2~{S},4~{R},5~{E})-5-[(5~{S})-5-azanyl-6,6-bis(oxidanyl)hexyl]iminohexane-1,2,4-triol'>I2F</scene></td></tr>
-
[[Category: Dobritzsch, D]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qxf OCA], [https://pdbe.org/7qxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qxf RCSB], [https://www.ebi.ac.uk/pdbsum/7qxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qxf ProSAT]</span></td></tr>
-
[[Category: Engel, S]]
+
</table>
-
[[Category: Widersten, M]]
+
== Function ==
 +
[https://www.uniprot.org/uniprot/FSAA_ECOLI FSAA_ECOLI] Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone (DHA) and D-glyceraldehyde 3-phosphate via an aldolization reaction. Can utilize several aldehydes as acceptor compounds in vitro, and hydroxyacetone (HA) or 1-hydroxy-butan-2-one as alternative donor substrate. Is also able to catalyze the direct stereoselective self-aldol addition of glycolaldehyde to furnish D-(-)-threose, and cross-aldol reactions of glycolaldehyde to other aldehyde acceptors. Is not able to cleave fructose, fructose 1-phosphate, glucose 6-phosphate, sedoheptulose 1,7-bisphosphate, xylulose 5-phosphate, ribulose 5-phosphate, and fructose 1,6-bisphosphate; cannot use dihydroxyacetone phosphate as donor compound nor D-glyceraldehyde as acceptor. Does not display transaldolase activity.<ref>PMID:11120740</ref> [HAMAP-Rule:MF_00496]<ref>PMID:17985886</ref> <ref>PMID:19554584</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Escherichia coli]]
 +
[[Category: Large Structures]]
 +
[[Category: Dobritzsch D]]
 +
[[Category: Engel S]]
 +
[[Category: Widersten M]]

Current revision

Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand

PDB ID 7qxf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7qxf"
Personal tools