7y5o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human CAF-1 core complex in spacegroup P21== | |
| - | + | <StructureSection load='7y5o' size='340' side='right'caption='[[7y5o]], [[Resolution|resolution]] 3.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7y5o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y5O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.57Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y5o OCA], [https://pdbe.org/7y5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y5o RCSB], [https://www.ebi.ac.uk/pdbsum/7y5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y5o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAF1B_HUMAN CAF1B_HUMAN] Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.<ref>PMID:9813080</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu CP]] | ||
| + | [[Category: Wang MZ]] | ||
| + | [[Category: Xu RM]] | ||
Current revision
Crystal structure of human CAF-1 core complex in spacegroup P21
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Categories: Homo sapiens | Large Structures | Liu CP | Wang MZ | Xu RM
