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8day
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of DMATS1 prenyltransferase in complex with L-Tyr and DMSPP== | |
| - | + | <StructureSection load='8day' size='340' side='right'caption='[[8day]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8day]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_fujikuroi Fusarium fujikuroi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DAY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DST:DIMETHYLALLYL+S-THIOLODIPHOSPHATE'>DST</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8day FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8day OCA], [https://pdbe.org/8day PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8day RCSB], [https://www.ebi.ac.uk/pdbsum/8day PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8day ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DMAT1_GIBF5 DMAT1_GIBF5] Dimethylallyltryptophan synthase; part of the DMATS1 gene cluster that mediates the biosynthesis of a reversely N-prenylated monomeric L-tryptophan (r-N-DMAT) (PubMed:28295904). The main product of the cluster is the r-N-DMAT produced by the dimethylallyltryptophan synthase DMATS1 and it remains unclear whether this metabolite undergoes further modifications when silent gene clusters are activated (PubMed:28295904). The acetylated form of r-N-DMAT, ac-r-N-DMAT, is also produced (PubMed:28295904). The roles of the cytochrome P450 monooxygenase FFUJ_09176 and the methyltransferase FFUJ_09178 have still to be elucidated (Probable).<ref>PMID:28295904</ref> <ref>PMID:28295904</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fusarium fujikuroi]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Christianson DW]] | ||
| + | [[Category: Eaton SA]] | ||
| + | [[Category: Ronnebaum TA]] | ||
| + | [[Category: Roose BW]] | ||
Current revision
Crystal Structure of DMATS1 prenyltransferase in complex with L-Tyr and DMSPP
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